Thread View: alt.bio.hackers
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Started by Louis Hom
Sun, 09 Jun 1996 00:00
Catalytic Ab's & Disease
Author: Louis Hom
Date: Sun, 09 Jun 1996 00:00
Date: Sun, 09 Jun 1996 00:00
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Does anyone know of a documented case where a disease is caused by the catalytic activity of a spontaneously occurring antibody (i.e., not engineered)? -- _______________________________________________________________________________ Lou Hom >K '93 "If brevity be the soul of wit, lhom@nature.berkeley.edu play on!" http://www.ocf.berkeley.edu/~lhom
Re: Catalytic Ab's & Disease
Author: Steven Striepeke
Date: Mon, 10 Jun 1996 00:00
Date: Mon, 10 Jun 1996 00:00
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Wouldn't the organism producing the catalytic antibody have to be induced to cause proliferation of that antibody in order for it to be a problem? It also seems unlikey that medical practioners would recognize the problem as a catalytic antibody - autoimmune disorders have just barely been accaepted. Louis Hom (lhom@nature.berkeley.edu) wrote: : Does anyone know of a documented case where a disease is caused by the : catalytic activity of a spontaneously occurring antibody (i.e., not : engineered)? : -- : _______________________________________________________________________________ : Lou Hom >K '93 "If brevity be the soul of wit, : lhom@nature.berkeley.edu play on!" : http://www.ocf.berkeley.edu/~lhom
Re: Catalytic Ab's & Disease
Author: matt szap
Date: Fri, 14 Jun 1996 00:00
Date: Fri, 14 Jun 1996 00:00
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I know of nothing documented regarding etiology
via catalytic antibodies. Although the assay would
have to be set up to be looking for evidence
of catalysis of some sort. This is an interesting
question, however-- what would the catalysis be?
--proteolysis? oligosacch. cleavage? I believe
they exist only through man-made tinkering through
the wizardry of Schultz and Lerner's bio-engineering.
Are there any that exist "naturally"? don't know.
The contents of this message express only the sender's opinion.
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my employer, Merck & Co., Inc. All responsibility for the statements
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