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3 messages
3 total messages Started by Louis Hom Sun, 09 Jun 1996 00:00
Catalytic Ab's & Disease
#25
Author: Louis Hom
Date: Sun, 09 Jun 1996 00:00
9 lines
961 bytes
Does anyone know of a documented case where a disease is caused by the
catalytic activity of a spontaneously occurring antibody (i.e., not
engineered)? 
-- 
_______________________________________________________________________________
Lou Hom >K '93		       	    	"If brevity be the soul of wit, 
lhom@nature.berkeley.edu  			   play on!" 
http://www.ocf.berkeley.edu/~lhom	 
Re: Catalytic Ab's & Disease
#23
Author: Steven Striepeke
Date: Mon, 10 Jun 1996 00:00
17 lines
1445 bytes
Wouldn't the organism producing the catalytic antibody have to be induced 
to cause proliferation of that antibody in order for it to be a 
problem? It also seems unlikey that medical practioners would recognize 
the problem as a catalytic antibody - autoimmune disorders have just 
barely been accaepted.


Louis Hom (lhom@nature.berkeley.edu) wrote:
: Does anyone know of a documented case where a disease is caused by the
: catalytic activity of a spontaneously occurring antibody (i.e., not
: engineered)? 
: -- 
: _______________________________________________________________________________
: Lou Hom >K '93		       	    	"If brevity be the soul of wit, 
: lhom@nature.berkeley.edu  			   play on!" 
: http://www.ocf.berkeley.edu/~lhom	 
Re: Catalytic Ab's & Disease
#24
Author: matt szap
Date: Fri, 14 Jun 1996 00:00
19 lines
1531 bytes
I know of nothing documented regarding etiology
via catalytic antibodies. Although the assay would
have to be set up to be looking for evidence 
of catalysis of some sort.  This is an interesting
question, however-- what would the catalysis be?
--proteolysis?  oligosacch. cleavage?  I believe
they exist only through man-made tinkering through
the wizardry of Schultz and Lerner's bio-engineering.  
Are there any that exist "naturally"?  don't know.




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