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Article #2122Re: Does HIV kill cells?
From: Matthew P Wiener
Date: Thu, 24 Mar 1994 14:18
Date: Thu, 24 Mar 1994 14:18
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In article <2mrn44$bl4@nntp2.Stanford.EDU>, ladasky@leland (John Ladasky) writes: > I've heard of two mechanisms by which indirect cell death >might occur in AIDS. The first involves soluble gp120. [...] > Sorry, I'm at home now and don't have the references handy. >But there is a nice mini-review/commentary article in a recent >Immunology Today called, "Immune Response to HIV - Helpful or >Harmful?" It covers the gp120/ anti-gp120 hypothesis. One version--perhaps worth calling a third mechanism--of this is Hoffman's network theory. There is surprising homology between gp120 and MHC(II), which is expressed on T-cells. Hoffman theorizes that anti-gp120 antibodies also attack MHC(II) T-cells. -- -Matthew P Wiener (weemba@sagi.wistar.upenn.edu)
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X-Google-Language: ENGLISH,ASCII-7-bit X-Google-Thread: 107c0a,1b241de11115c682 X-Google-Attributes: gid107c0a,public X-Google-Thread: 103cc5,1b241de11115c682 X-Google-Attributes: gid103cc5,public X-Google-Thread: 1119a6,1b241de11115c682 X-Google-Attributes: gid1119a6,public X-Google-Thread: 11045f,1b241de11115c682 X-Google-Attributes: gid11045f,public X-Google-Thread: f8e22,1b241de11115c682 X-Google-Attributes: gidf8e22,public X-Google-Thread: ff2c4,1b241de11115c682 X-Google-Attributes: gidff2c4,public X-Google-ArrivalTime: 1994-03-24 06:18:41 PST Path: arc1-ca.pugleaf.net!gmd.de!xlink.net!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!agate!msuinfo!netnews.upenn.edu!news From: weemba@sagi.wistar.upenn.edu (Matthew P Wiener) Newsgroups: bionet.general,bionet.cellbiol,bionet.molbio.hiv,bionet.virology,bionet.immunology,sci.bio Subject: Re: Does HIV kill cells? Followup-To: bionet.general Date: 24 Mar 1994 14:18:41 GMT Organization: The Wistar Institute of Anatomy and Biology Lines: 15 Message-ID: <2ms7g1$jn1@netnews.upenn.edu> References: <1994Mar24.085208.16835@leeds.ac.uk> <2mrn44$bl4@nntp2.Stanford.EDU> Reply-To: weemba@sagi.wistar.upenn.edu (Matthew P Wiener) NNTP-Posting-Host: sagi.wistar.upenn.edu In-reply-to: ladasky@leland.Stanford.EDU (John Ladasky)