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Highlights of recent patent applications on next generation sequencing

1. Terminal tagging oligoribonucleotide (rTTO) to join a DNA sequence tag to the 3′-termini of first-strand cDNA molecules
2. A ligation-based method and a kit for preparing a template for next generation sequencing
3. Next generation sequencing method for noninvasive prenatal diagnostics
4. High-throughput next generation sequencing DNA markers for treating, diagnosing, and prognosing lung cancer
5. Next generation sequencing method of predicting the risk of a patient for developing COX-2 inhibitor lumiracoxib induced hepatotoxicity
6. Next generation sequencing method for determining the primary site of a cancer of unknown primary site (CUP)
7. Next generation sequencing method for diagnosing Noonan-like syndrome with loose anagen hair
8. Next generation sequencing method for the diagnosis of Alzheimer’s disease
9. Method for high throughput paired-end sequencing of large-insert clone libraries for next generation sequencing
10. Next generation sequencing method for determining the increased risk for developing degenerative neurological or psychiatric diseases
11. Identification of fetal nucleic acid fraction in a mixture of fetal and maternal nucleic acids using next generation sequencing
12. Next generation sequencing method for predicting the risk of developing late onset Alzheimer’s disease
13. Whole genome sequencing methods for identifying polymorphisms in blood sample
14. Next generation sequencing methods for diagnosing presence or increased risk of developing an autism spectrum disorder
15. Next generation sequencing method for determining the genome of an unborn fetus of a pregnant female

Details: http://www.sciclips.com/sciclips/biomarker-news.do