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Article #375

Panseq - genomic comparison software

#375
From: kropinsk
Date: Tue, 17 Aug 2010 14:04
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Panseq (http=3A//76=2E70=2E11=2E198/claing/panseq/panseq=5Fhome=2Ecgi)
- a group of tools=2C developed by Chad Laing (Public Health Agency of C=
anada) =A0for
the analysis of the =27pan genome=27 of a group of genomic sequences=2E =
The
pan-genome of a bacterial species consists of a core genome and an acces=
sory
gene pool=2C the latter of which allows subpopulations of the organism t=
o adapt
to specific environments=2E These include =93Novel Region Finder=94=2C w=
hich will find
sequences that are unique to a strain or group of strains with respect t=
o
another strain or group of strains=2E =93Core/Accessory Genome Analysis=94=
 will
define the core and accessory genome of a group of strains=2C based on t=
he user
configurable parameters of region size and percent sequence identity=2E =
Outputs
of this feature include concatenated core genomes for each sequence exam=
ined=2C a
tab-delimited table depicting the presence / absence of each accessory r=
egion
among all the sequences examined=2C a tab-delimited table depicting each=
 SNP
among all the sequences examined and NEXUS format files of both the core=
 and
accessory genome=2E =93Loci Selector=94 determines the most variable and=

discriminatory loci from a group=2E=A0

=A0

This site can also
be accessed at=3A http//molbiol-tools=2Eca/Genomics=2Ehtm



Andrew M=2E Kropinski
Research Scientist =26 Program Lead=2C Host =26 Pathogen Determinants=2C=
 Laboratory for Foodborne Zoonoses
Adjunct Professor =2C Microbiology =26 Immunology=2C Queen=27s Universit=
y
Adjunct Professor=2C Molecular =26 Cellular Biology=2C University of Gue=
lph

URL=3A Online Analysis Tools (http=3A//molbiol-tools=2Eca)



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=3Cp class=3D=22MsoNormal=22=3E=3Cspan style=3D=22=22=3EPanseq (=3Ca hre=
f=3D=22http=3A//76=2E70=2E11=2E198/claing/panseq/panseq=5Fhome=2Ecgi=22=3E=
http=3A//76=2E70=2E11=2E198/claing/panseq/panseq=5Fhome=2Ecgi=3C/a=3E)
- a group of tools=2C developed by =3Cem=3E=3Cspan style=3D=22font-famil=
y=3A Arial=3B font-style=3A normal=3B=22=3EChad Laing (Public Health Age=
ncy of Canada)=3C/span=3E=3C/em=3E=3Ci style=3D=22=22=3E =3Cspan style=3D=
=22=22=3E=26nbsp=3B=3C/span=3E=3C/i=3Efor
the analysis of the =27pan genome=27 of a group of genomic sequences=2E =
The
pan-genome of a bacterial species consists of a core genome and an acces=
sory
gene pool=2C the latter of which allows subpopulations of the organism t=
o adapt
to specific environments=2E These include =93Novel Region Finder=94=2C w=
hich will find
sequences that are unique to a strain or group of strains with respect t=
o
another strain or group of strains=2E =93Core/Accessory Genome Analysis=94=
 will
define the core and accessory genome of a group of strains=2C based on t=
he user
configurable parameters of region size and percent sequence identity=2E =
Outputs
of this feature include concatenated core genomes for each sequence exam=
ined=2C a
tab-delimited table depicting the presence / absence of each accessory r=
egion
among all the sequences examined=2C a tab-delimited table depicting each=
 SNP
among all the sequences examined and NEXUS format files of both the core=
 and
accessory genome=2E =93Loci Selector=94 determines the most variable and=

discriminatory loci from a group=2E=26nbsp=3B=3Co=3Ap=3E=3C/o=3Ap=3E=3C/=
span=3E=3C/p=3E

=3Cp class=3D=22MsoNormal=22=3E=3Cspan style=3D=22=22=3E=3Co=3Ap=3E=26nb=
sp=3B=3C/o=3Ap=3E=3C/span=3E=3C/p=3E

=3Cp class=3D=22MsoNormal=22=3E=3Cspan style=3D=22=22=3EThis site can al=
so
be accessed at=3A http//molbiol-tools=2Eca/Genomics=2Ehtm=3Co=3Ap=3E=3C/=
o=3Ap=3E=3C/span=3E=3C/p=3E

=3Cbr=3E=3Cbr=3EAndrew M=2E Kropinski=3Cbr=3EResearch Scientist =26amp=3B=
 Program Lead=2C Host =26amp=3B Pathogen Determinants=2C Laboratory for =
Foodborne Zoonoses=3Cbr=3EAdjunct Professor =2C Microbiology =26amp=3B I=
mmunology=2C Queen=27s University=3Cbr=3EAdjunct Professor=2C Molecular =
=26amp=3B Cellular Biology=2C University of Guelph=3Cbr=3E=3Cbr=3EURL=3A=
 Online Analysis Tools (http=3A//molbiol-tools=2Eca)=3Cbr=3E=3Cbr=3E

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