🚀 go-pugleaf

RetroBBS NetNews Server

Inspired by RockSolid Light RIP Retro Guy

Article View: bionet.molbio.evolution
Article #6583

Re: Query about long stretches of sequence identity

#6583
From: Ron DeBry
Date: Thu, 26 Sep 1991 20:31
19 lines
1601 bytes
In article <CMM.0.88.685908696.kristoff@genbank.bio.net> kristoff@GENBANK.BIO.NET (Dave Kristofferson) writes:
>What is the longest stretch of sequence *identity,* not just similarity, 
known between the mouse and bovine versions of the same protein?

As a minimum, start with 135 amino acids.  This is the length of histone
H3.  All mammals have two forms differing by one serine-cystein change
at position 96.  Interestingly, in human and cow, 80% of the protein is
H3.1, but in rodents 80% of the protein is H3.2.

The other histones are similar in size, and probably also have identical
variants in both cows and rodents.

I don't have the exact reference off the top of my head, but every 2-3
years Dan Wells publishes a big compilation of all histone sequences in
the supplement to NAR.

Ron DeBry

debry@ds1.scri.fsu.edu
Technical Details
Message-ID: <4438@sun13.scri.fsu.edu>
Path: arc1-ca.pugleaf.net!gmdzi!unido!fauern!ira.uka.de!sol.ctr.columbia.edu!zaphod.mps.ohio-state.edu!rpi!uwm.edu!psuvax1!ukma!nsisrv!kong!mimsy!haven.umd.edu!uflorida!mailer.cc.fsu.edu!sun13!ds1.scri.fsu.edu!debry
References: <CMM.0.88.685908696.kristoff@genbank.bio.net>

Show Full Headers
Complete Article Headers
X-Google-Language: ENGLISH,ASCII-7-bit
X-Google-Thread: 10a7a9,251186ca98aa5006,start
X-Google-Attributes: gid10a7a9,public
X-Google-ArrivalTime: 1991-09-26 21:39:30 PST
Path: arc1-ca.pugleaf.net!gmdzi!unido!fauern!ira.uka.de!sol.ctr.columbia.edu!zaphod.mps.ohio-state.edu!rpi!uwm.edu!psuvax1!ukma!nsisrv!kong!mimsy!haven.umd.edu!uflorida!mailer.cc.fsu.edu!sun13!ds1.scri.fsu.edu!debry
From: debry@ds1.scri.fsu.edu (Ron DeBry)
Newsgroups: bionet.molbio.evolution
Subject: Re: Query about long stretches of sequence identity
Message-ID: <4438@sun13.scri.fsu.edu>
Date: 26 Sep 91 20:31:45 GMT
References: <CMM.0.88.685908696.kristoff@genbank.bio.net>
Sender: news@sun13.scri.fsu.edu
Distribution: bionet
Organization: SCRI, Florida State University
Lines: 19