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Article #6594

Re: longest matching sequence

#6594
From: Tom Schneider
Date: Mon, 30 Sep 1991 13:26
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In article <9109261841.AA15052@bambi.ccs.fau.edu> tomh@BAMBI.CCS.FAU.EDU (Tom Holroyd)
writes:
> Waterman, M.S., L. Gordon, and R. Arratia.  Phase transitions in
> sequence matches and nucleic acid structure.  PNAS 84: 1239-1243, 1987.

> The phase transition they refer to is
> that the minimum energy, and thus the alignment selected, changes
> from a linear to a logarithmic relationship with the mismatch penalty.

How could an energy be involved when a human compares two sequences (other than
the actions that the human takes)?  That is, although I'm sure it takes energy
to compare sequences, what could this possibly mean in terms of the molecules
involved?

  Tom Schneider
  National Cancer Institute
  Laboratory of Mathematical Biology
  Frederick, Maryland  21702-1201
  toms@ncifcrf.gov
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From: toms@fcs260c2.ncifcrf.gov (Tom Schneider)
Newsgroups: bionet.molbio.evolution
Subject: Re: longest matching sequence
Message-ID: <2390@fcs280s.ncifcrf.gov>
Date: 30 Sep 91 13:26:22 GMT
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