Endothelin: PMAP

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1 total messages Started by j_thomas Thu, 17 Feb 2011 04:38

#155

Author: j_thomas
Date: Thu, 17 Feb 2011 04:38

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Endothelins are proteins that constrict blood vessels and raise blood
pressure. They are normally kept in balance by other mechanisms, but
when they are over-expressed, they contribute to high blood pressure
(hypertension) and heart disease.The ubiquitous distribution of
endothelin peptides and receptors implicates its involvement in a wide
variety of physiological and pathological processes in the body. Among
numerous diseases potentially occurring from endothelin dysregulation
are: several types of cancer; cerebral vasospasm following
subarachnoid hemorrhage; arterial hypertension and other
cardiovascular disorders; pain mediation



http://www.biosolutions.info/2011/02/endothelin-pmap.html

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