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NIH GUIDE - Vol. 26, No. 30 - September 5, 1997

$$INDEX BEGIN *******************************************************

                               NOTICES

$$INDEX N1 **********************************************************

FINDINGS OF SCIENTIFIC MISCONDUCT
Department of Health and Human Services
INDEX:  DEPARTMENT OF HEALTH AND HUMAN SERVICES

$$INDEX N2 **********************************************************

IMMIGRANT ELIGIBILITY PROVISIONS OF THE PERSONAL RESPONSIBILITY AND
WORK OPPORTUNITY RECONCILIATION ACT OF 1996 (PRWORA), P.L. 103-193
National Institutes of Health
INDEX:  NATIONAL INSTITUTES OF HEALTH

$$INDEX N3 **********************************************************

NOTICE OF LEGISLATIVE AND ADMINISTRATIVE CHANGES
National Institutes of Health
INDEX:  NATIONAL INSTITUTES OF HEALTH

$$INDEX N4 **********************************************************

MUCOSAL IMMUNITY IN PATHOGENESIS/PREVENTION OF HUMAN DISEASE
(PA-97-073)
National Institutes of Health
INDEX:  NATIONAL INSTITUTES OF HEALTH

               NOTICES OF AVAILABILITY (RFPs/RFAs/PAs)

$$INDEX R1 11/25/97 *************************************************

CANCER RESEARCH NETWORK ACROSS HEALTH CARE SYSTEMS (RFA CA-97-017)
National Cancer Institute
INDEX:  CANCER

$$INDEX R2 11/25/97 *************************************************

LONG-TERM CANCER SURVIVORS: RESEARCH INITIATIVES (RFA CA-97-018)
National Cancer Institute
INDEX:  CANCER

$$INDEX P1 **********************************************************

HIV PATHOGENESIS IN WOMEN'S INTERAGENCY HIV STUDY (WIHS) (PA-97-105)
National Institute of Allergy and Infectious Diseases
National Institute of Child Health and Human Development
National Institute on Drug Abuse
National Cancer Institute
National Institute of Dental Research
National Institute of Diabetes and Digestive and Kidney Diseases
National Institute of Neurological Disorders and Stroke
Office of Research Women's Health
INDEX:  ALLERGY, INFECTIOUS DISEASES; CHILD HEALTH, HUMAN
DEVELOPMENT; DRUG ABUSE; CANCER; DENTAL RESEARCH; DIABETES,
DIGESTIVE, KIDNEY DISEASES; NEUROLOGICAL DISORDERS, STROKE; WOMEN'S
HEALTH

The NIH GUIDE is available electronically via LISTSERV subscription,
and is also on the NIH gopher (gopher.nih.gov) and the NIH website
(http://www.nih.gov). Alternative access is through the NIH Grant
Line via modem (data line 301/402-2221); contact Dr. John James
at 301/435-2801 for details on the NIH Grant Line.

All competing grant applications submitted to the National Institutes
of Health must be sent to:

DIVISION OF RESEARCH GRANTS
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)

ASKNIH is a service of the Division of Extramural Outreach &
Information Resources, Office of Extramural Research, Office of the
Director, NIH.  ASKNIH is the point of contact for obtaining general
information about NIH extramural research & research training
programs, requesting publications, and learning more about obtaining
the NIH GUIDE and other information on the NIH web site.  ASKNIH is
also the contact aid which organizations should request application
kits and forms.

ASKNIH
NATIONAL INSTITUTES OF HEALTH
EMAIL:  ASKNIH@odrockm1.od.nih.gov
FAX:  (301) 480-0525
TELEPHONE:  (301) 435-0714

INQUIRIES ABOUT THE NOTICES, PAs, AND RFAs IN THIS PUBLICATION SHOULD
BE DIRECTED TO THE NIH STAFF MEMBER IDENTIFIED AT THE END OF EACH
ITEM.

THE PHS STRONGLY ENCOURAGES ALL GRANT AND CONTRACT RECIPIENTS TO
PROVIDE A SMOKE-FREE WORKPLACE AND PROMOTE THE NON-USE OF ALL TOBACCO
PRODUCTS.  IN ADDITION, PUBLIC LAW 103-227, THE PRO-CHILDREN ACT OF
1994, PROHIBITS SMOKING IN CERTAIN FACILITIES (OR IN SOME CASES, ANY
PORTION OF A FACILITY) IN WHICH REGULAR OR ROUTINE EDUCATION,
LIBRARY, DAY CARE, HEALTH CARE OR EARLY CHILDHOOD DEVELOPMENT
SERVICES ARE PROVIDED TO CHILDREN.  THIS IS CONSISTENT WITH THE PHS
MISSION TO PROTECT AND ADVANCE THE PHYSICAL AND MENTAL HEALTH OF THE
AMERICAN PEOPLE.

$$INDEX END *********************************************************

                               NOTICES

$$N1 BEGIN **********************************************************

FINDINGS OF SCIENTIFIC MISCONDUCT

NIH GUIDE, Volume 26, Number 30, September 5, 1997

P.T. 34; K.W. 1014004, 1014006

Department of Health and Human Services

Notice is hereby given that the Office of Research Integrity (ORI)
has made a final finding of scientific misconduct in the following
cases:

Jill A. London, Ph.D., University of Connecticut Health Center:
Based upon a report from the University of Connecticut Health Center
as well as information obtained by the Office of Research Integrity
(ORI) during its oversight review, ORI found that Dr. London, former
Assistant Professor, Department of Biostructure and Function, School
of Dental Medicine, University of Connecticut Health Center, engaged
in scientific misconduct by intentionally falsifying data in
conjunction with applying for and reporting research supported by the
National Institute of Neurological Disorders and Stroke (NINDS) and
the National Institute on Deafness and Other Communication Disorders
(NIDCD), National Institutes of Health (NIH).

Specifically, ORI found that Dr. London~s grant applications and
articles contained numerous falsifications, including

(1) Figures 6, 7, and 8 in a paper (London, J.A. & Cohen, L.B.  ~High
time resolution, multi-site optical measurement of vertebrate
somatosensory cortex during epileptiform discharges and vertebrate
gustatory cortex.~  Optical Methods in Neurobiology, pp. 61-78,
1988.) prepared for the 11th Annual Meeting of the European
Neuroscience Association (hereafter referred to as the European
Neuroscience paper) that cited support by NINDS, NIH grants R01
NS08437 and P01 NS16993;

(2) Figure 1A in a paper (London, J.A., ~Optical recording of
activity in the hamster gustatory cortex elicited by electrical
stimulation of the tongue.~  Chemical Senses 15:137-143, 1990.) that
cited support by NINDS, NIH grants R01 NS08437 and P01 NS16993;
Figure 1A was found to be very similar or identical to Figure 7 of
the European Neuroscience paper in #1 above;

(3) Figures 10 to 13 in grant application 2 P50 DC00168-14,
~Connecticut Chemosensory Clinical Research Center,~ submitted to
NIDCD, NIH on January 28, 1994; these figures also appear as Figures
4 to 7 in grant application 2 P50 DC00168-14A1, submitted to NIDCD,
NIH on September 28, 1994;

(4) Figures 2, 8, and 9 in grant application 1 R01 DC01752-01,
~Optical recording of hamster gustatory cortex activity,~ submitted
to NIDCD, NIH on January 29, 1992; these figures were the same as
Figures 11, 12, and 13, respectively, in grant application 2 P50
DC00168-14 (see #3 above);

(5) figures supplied for Figures 1 and 3 in grant application 1 F32
NS09601-01, ~Modular response patterns in hamster gustatory cortex,~
submitted to NINDS, NIH on August 3, 1993; these figures were the
same as Figures 10 and 11, respectively, in grant application 2 P50
DC00168-14 (see #3 above);

(6) Figure 3 of a handout that Dr. London provided during an NIH site
visit on April 25, 1994, conducted in conjunction with the review of
grant application 2 P50 DC00168-14; the top and bottom portions of
Figure 3 of the site visit handout were very similar or identical to
Figures 6 and 7, respectively, of the European Neuroscience paper
(see #1 above), and approximately 115 of the 125 traces appearing in
each of the figures showed identities, with one or two ~active~
traces being identical;

(7) Figures 1, 2, and 3 in a paper (London, J.A. & Wehby, R.G.
~Classification of inhibitory responses of hamster gustatory cortex.~
Brain Research 666:270-274, 1994.) that cited support by NIDCD, NIH
grants P50 DC00168 and T32 DC00025; and

(8) nine figures included in a manuscript (London, J.A. & Wehby, R.G.
~Excitatory neural responses in the hamster gustatory cortex.~
Submitted to Brain Research, 1996.) that cited support by NIDCD, NIH
grants P50 DC00168 and T32 DC00025.

Dr. London has accepted the ORI finding and has entered into a
Voluntary Exclusion Agreement with ORI in which she has voluntarily
agreed, for a period of five (5) years, beginning August 8, 1997:

(1) to exclude herself from any contracting or subcontracting with
any agency of the United States Government and from eligibility for,
or involvement in, nonprocurement transactions (e.g., grants and
cooperative agreements) of the United States Government as defined in
45 C.F.R. Part 76 (Debarment Regulations); and

(2) to exclude herself from serving in any advisory capacity to the
Public Health Service (PHS), including but not limited to service on
any PHS advisory committee, board, and/or peer review committee, or
as a consultant.

Dr. London is required to submit a letter to

o  Chemical Senses requesting a retraction of the following article:
London, J.A.  ~Optical recording of activity in the hamster gustatory
cortex elicited by electrical stimulation of the tongue.~  Chemical
Senses 15:137-143, 1990;

o  Brain Research requesting a retraction of the following article:
London, J.A., & Wehby, R.G.  ~Classification of inhibitory responses
of the hamster gustatory cortex.~  Brain Research 666:270-274, 1994;
and

o  Optical Methods in Neurobiology requesting a retraction of Section
V, Results -- Hamster of the following article:  London, J.A., &
Cohen, L.B.  ~High time resolution, multi-site optical measurement of
vertebrate somatosensory cortex during epileptiform discharges and
vertebrate gustatory cortex.~  Optical Methods in Neurobiology, pp.
61-78, 1988, prepared for the 11th Annual Meeting of the European
Neuroscience Association.

Shoushu Jiao, M.D., University of Wisconsin:  Based upon reports from
the University of Wisconsin as well as information obtained by the
Office of Research Integrity (ORI) during its oversight review, ORI
found that Dr. Jiao, former Research Associate, Department of
Pediatrics, University of Wisconsin, engaged in scientific misconduct
by falsifying and creating laboratory records while conducting
biomedical research.  The data in these records were reported in a
National Institute of Neurological Disorders and Stroke (NINDS),
National Institutes of Health (NIH) grant application to support a
request for Public Health Service (PHS) funding.  Based on the
factual findings in the reports, the following article has been
retracted:  Jiao, S., Gurevich, V., & Wolff, J.A.  ~Long-term
correction of rat model of Parkinson~s disease by gene therapy.~
Nature 362:450-453, 1993.

Dr. Jiao has entered into a Voluntary Exclusion Agreement with ORI in
which he has voluntarily agreed:

(1) to exclude himself from serving in any advisory capacity to PHS,
including but not limited to service on any PHS advisory committee,
board, and/or peer review committee, or as a consultant for a period
of four (4) years, beginning on August 8, 1997.

(2) to exclude himself from any contracting or subcontracting with
any agency of the United States Government and from eligibility for,
or involvement in, nonprocurement transactions (e.g., grants and
cooperative agreements) of the United States Government as defined in
45 C.F.R. Part 76 (Debarment Regulations) for a period of three (3)
years, beginning on August 8, 1997; and

(3) that any institution that submits an application for PHS support
for a research project on which Dr. Jiao~s participation is proposed,
uses him in any capacity on PHS supported research, or submits a
report of PHS-funded research in which he is involved must
concurrently submit a plan for supervision of his duties to the
funding agency for approval for a period of one (1) year following
the three (3) year exclusion.  The supervisory plan must be designed
to ensure the scientific integrity of Dr. Jiao~s research
contribution.  The institution also must submit a copy of the
supervisory plan to ORI.

INQUIRIES

For further information contact:

Acting Director, Division of Research Investigations
Office of Research Integrity
5515 Security Lane, Suite 700
Rockville, MD  20852
Telephone:  (301) 443-5330

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$$N2 BEGIN **********************************************************

IMMIGRANT ELIGIBILITY PROVISIONS OF THE PERSONAL RESPONSIBILITY AND
WORK OPPORTUNITY RECONCILIATION ACT of 1996 (PRWORA), P.L. 103-193

NIH GUIDE, Volume 26, Number 30, September 5, 1997

P.T. 34; K.W. 1004006

National Institutes of Health

This notice provides information on the Personal Responsibility and
Work Opportunity Reconciliation Act of 1996 (PRWORA), P.L. 104-193,
which restricts the access of certain categories of immigrants to
specified Federal benefits. Since this Act  affects some benefits
administered by the Department of Health and Human Services (HHS),
HHS has issued guidance on certain immigrant eligibility provisions
of the PRWORA.

Effective August 26, 1997, HHS has adopted an interpretation on
Section 403 of the PRWORA.  Section 403 of  PRWORA bars most
qualified aliens who enter the U.S. on or after the enactment (August
22, 1996) from being eligible for ~Federal means-tested public
benefits~ for five years.  Under HHS interpretation, ~Federal means-
tested public benefits~ include only  those benefits provided under
the means-tested, mandatory spending programs. The only HHS programs
meeting this definition include Medicaid and Temporary Assistance for
Needy Families (TANF) Block Grants (the successor to the AFDC
program).  No NIH programs meet the  ~Federal means-tested public
benefits~ criterion for purposes of PRWORA.  Therefore, all qualified
aliens, regardless of when they entered the U.S., may continue to be
eligible to participate in programs supported by the National
Institutes of Health if they meet other program requirements.

Guidance on other immigration-related issues is still under
consideration.  HHS is currently analyzing these complex provisions
to determine their impact on numerous programs and services.  Further
information will be provided as issues are resolved.

For detailed information concerning this notice, please refer to The
Federal Register, Volume 62, Number 165, Pages 45,256 - 45,258,
August 26, 1997.  If additional questions remain, please contact your
awarding grants or contracts management office in the NIH Institutes
and Centers.

$$N2 END ************************************************************

$$N3 BEGIN **********************************************************

NOTICE OF LEGISLATIVE AND ADMINISTRATIVE CHANGES

NIH GUIDE, Volume 26, Number 30, September 5, 1997

P.T. 34; K.W. 1014006

National Institutes of Health

The purpose of this Notice is to provide information on recent
legislative changes, administrative requirements and Executive Orders
that impact NIH grantees.  There are no additional reporting
requirements required by these changes.

1.  Military Recruiting and Reserve Officer Training Corps Program
Access to Institutions of Higher Education

Effective March 29, 1997, the Department of Defense adopted an
interim rule to implement Section 514 of the Omnibus Consolidated
Appropriations Act of 1997 (see ~NOTICE OF LEGISLATIVE MANDATES
CONTAINED IN THE OMNIBUS CONSOLIDATED FISCAL YEAR 1997 APPROPRIATIONS
ACT, P.L. 104-208, SIGNED SEPTEMBER 30, 1996", NIH GUIDE, Volume 26,
Number 4, February 7, 1997).

The rule prohibits NIH from providing funds to educational
institutions that have a policy or practice (regardless of when
implemented) that either prohibits, or in effect prevents (1) the
maintaining, establishing, or operation of a unit of the Senior
Reserve Officer Training Corps at the covered education entity; or
(2) a student at the covered educational entity from enrolling in a
unit of the Senior Reserve Officer Training Corps at another
institution of higher education.  Under the same rule, NIH is
prohibited from providing funds to educational institutions that have
a policy or practice that prohibits or prevents (1) entry to
campuses, or access to students (who are 17 years of age or older) on
campuses, for purposes of Federal military recruiting; or (2) access
by military recruiters for purposes of Federal military recruiting to
information pertaining to students (who are 17 years of age or older)
enrolled at the covered educational entity.

The adopted rule implements the law, and is effective March 29, 1997.
Additional information on this topic can be found at
gopher://gopher.legislate.com:70/11/regs/590/590178.

2.  Implementation of the President~s Welfare-to-Work Initiative for
Federal Grant Employees

On March 8, 1997, the President issued a memorandum to the heads of
the executive departments and agencies entitled "Government
Employment for Welfare Recipients."  This memorandum directs all
Federal agencies to hire people off the welfare rolls into available
job positions in the Government.  To supplement this initiative,
Federal agencies have been asked to encourage all  grantees and their
subrecipients to hire welfare recipients and to provide additional
training and/or mentoring to hired welfare recipients. Additional
information on the Welfare-to-Work initiative and hiring of welfare
recipients, including the allowability of training costs, available
Federal tax credits, and examples of successful private sector
initiatives, can be found at
http://www.whitehouse.gov/WH/EOP/OMB/html/fedreg/omb-not.html.

3.  Seat Belt Use by Grantees - Executive Order 13043

On April 16, 1997, the President issued Executive Order 13043,
"Increasing Seat Belt Use in the United States."  In support of this
Order, the NIH encourages all grantees to adopt and enforce on-the-
job seat belt policies and programs for their employees when
operating company-owned, rented, or personally owned vehicles.  The
text of the notice, and additional details on this issue can be found
at: gopher://gopher.legislate.com:70/11/regs/591/591354.

Appropriate links to related regulations and policies have been
provided with the copy of this notice published on the NIH Homepage.
If additional questions remain, please contact your awarding grants
or contracts management office in the NIH Institutes and Centers.

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$$N4 BEGIN **********************************************************

MUCOSAL IMMUNITY IN PATHOGENESIS/PREVENTION OF HUMAN DISEASE

NIH GUIDE, Volume 26, Number 30, September 5, 1997

PA NUMBER:  PA-97-073

P.T.

National Institutes of Health

This notice is an addendum to Program Announcement PA-97-073, MUCOSAL
IMMUNITY IN PATHOGENESIS/PREVENTION OF HUMAN DISEASE, which was
published in the NIH Guide for Grants and Contracts, Vol. 26, No. 23,
July 18, 1997.

The National Institute of Child Health and Human Development (NICHD)
is also a sponsor of this program announcement.  The NICHD was
inadvertently omitted from the PA.

The NICHD staff contact for electronic and telephone is listed below
and inquiries regarding programmatic (research scope and eligibility)
issues are encouraged.  The opportunity to clarify any issues or
answer questions from potential applicants is welcome.

National Institute of Child Health and Human Development
Allan Lock, D.V.M.
Telephone:  (301) 496-5541
FAX:  (301) 402-4083
Email:  LockA@hd01.nichd.nih.gov

$$N4 END ************************************************************

               NOTICES OF AVAILABILITY (RFPs/RFAs/PAs)

$$R1 BEGIN CA-97-017 FULL-TEXT **************************************

CANCER RESEARCH NETWORK ACROSS HEALTH CARE SYSTEMS

NIH GUIDE, Volume 26, Number 30, September 5, 1997

RFA AVAILABLE:  CA-97-017

P.T.

National Cancer Institute

Letter of Intent Receipt Date:  October 17, 1997
Application Receipt Date:  November 25, 1997

PURPOSE

A Request for Applications is available to encourage the expansion of
collaborative cancer research among health care provider
organizations that are oriented to community care,  have access to
large, stable and diverse patient populations and are able to take
advantage of existing integrated data-bases that can provide
patient-level information relevant to research studies on cancer
control and cancer-related population studies.  Health care provider
organizations range from traditional staff model health maintenance
organizations (HMO) to extended health care networks associated with
academic medical centers. A CRN would consist of a research network
of such health care provider organizations that possess in-house
clinical research capacity, that collaborate with other provider
organizations with such capacity, or with clinical researchers
affiliated with academic health centers. A CRN should consist of
diverse members drawn from a number of financially autonomous and
managerially distinct organizations. Up to two awards are
anticipated.  A total of  $16.8 million is set aside to fund
applications submitted in response to this solicitation (first year
funding is $4 million).

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas. This RFA,
CANCER RESEARCH NETWORK ACROSS HEALTH CARE SYSTEMS, is related to
multiply priority areas, including cancer surveillance and data
systems.  Potential applicants may obtain a copy of "Healthy People
2000" (Full Report:  Stock No. 017-001-00474-0 or Summary Report:
Stock No. 017-001-00473-1) through the Superintendent of Documents,
Government Printing Office, Washington, DC 20402-9325 (telephone
202-512-1800).

INQUIRIES

The RFA, which describes the research objectives, application
procedures, review considerations and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301-402-2221), and the NIH GOPHER (gopher.nih.gov),
and the NIH Website (http://www.nih.gov), and by mail and E-mail from
the program contact listed below.

Martin Brown, Ph.D.
Applied Research Branch
National Cancer Institute
6130 Executive Boulevard, Room 313
Bethesda, MD  20892-7344
Telephone:  (301) 496-5716
FAX:  (301) 435-3710
Email:  mb53o@nih.gov

$$R1 END ************************************************************

$$R2 BEGIN CA-97-018 FULL-TEXT **************************************

LONG-TERM CANCER SURVIVORS: RESEARCH INITIATIVES

NIH GUIDE, Volume 26, Number 30, September 5, 1997

RFA AVAILABLE:  CA-97-018

P.T.

National Cancer Institute

Letter of Intent Receipt Date:  October 24, 1997
Application Receipt Date:  November 25, 1997

PURPOSE

The National Cancer Institute invites research grant applications to
identify important areas that have an impact on long term survivors
of cancer.  The purpose of this RFA is to support research that will
lead to a decrease in the physiologic and psychological morbidity
associated with long term (more than 5 years) survival after cancer
treatment.  Questions related to the experience of the cancer
survivor encompassing both physiologic and psychological variables
are to be explored and interventions to promote positive outcomes
evaluated where appropriate.  This RFA is not intended to address
questions that explore differences between survivors and
non-survivors that may be linked to mechanisms of disease progression
or genetic predisposition.  The estimated funds (total costs)
available for the first year of support for awards under the RFA will
be $3,000,000.  Pending receipt of a sufficient number of
applications of high scientific merit, the NCI intends to fund a
total of approximately 12 to 15 awards in response to the RFA in
FY98. This RFA will use the National Institutes of Health (NIH)
Research Project Grant (R01), the Small Grant (R03) and the FIRST
(R29) award.  The total project period for an application submitted
in response to this RFA may not exceed 5 years.  The small grant
(R03) is limited to 2 years.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas. This RFA,
Long-Term Cancer Survivors: Research Initiatives, is related to the
priority area of long term and late effects of cancer and its
treatment.  Potential applicants may obtain a copy of "Healthy People
2000" (Full Report:  Stock No. 017-001-00474-0 or Summary Report:
Stock No. 017-001-00473-1) through the Superintendent of Documents,
Government Printing Office, Washington, DC 20402-9325 (telephone
202-512-1800).

INQUIRIES

The RFA, which describes the research objectives, application
procedures, review considerations and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301-402-2221), and the NIH GOPHER (gopher.nih.gov),
and the NIH Website (http://www.nih.gov), and by mail and E-mail from
the program contact listed below.

Claudette G. Varricchio DSN, RN, FAAN
Division of Cancer Prevention and Control
National Cancer Institute
6130 Executive Boulevard, Room 300
Bethesda, MD  20892-7340
Telephone:  (301) 496-8541
FAX:  (301) 496-8667
Email:  varriccc@dcpcepn.nci.nih.gov

$$R2 END ************************************************************

$$P1 BEGIN PA-97-105 FULL-TEXT **************************************

HIV PATHOGENESIS IN WOMEN'S INTERAGENCY HIV STUDY (WIHS)

NIH GUIDE, Volume 26, Number 30, September 5, 1997

PA AVAILABLE:  PA-97-105

P.T.

National Institute of Allergy and Infectious Diseases
National Institute of Child Health and Human Development
National Institute on Drug Abuse
National Cancer Institute
National Institute of Dental Research
National Institute of Diabetes and Digestive and Kidney Diseases
National Institute of Neurological Disorders and Stroke
Office of Research Women's Health

PURPOSE

The National Institute of Allergy and Infectious Diseases (NIAID),
the National Institute of Child Health and Human Development (NICHD),
the National Institute on Drug Abuse (NIDA), the National Cancer
Institute (NCI), the National Institute of Dental Research (NIDR),
the National Institute of Diabetes and Digestive and Kidney Diseases
(NIDDK),  the National Institute of Neurological Disorders and Stroke
(NINDS) and the Office of Research on Women's Health (ORWH) invite
applications for studies on HIV Pathogenesis in the Women's
Interagency HIV Study (WIHS).

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This Program
Announcement (PA), "HIV PATHOGENESIS IN WOMEN'S INTERAGENCY HIV STUDY
(WIHS)", is related to the priority area(s) of HIV infection.
Potential applicants may obtain a copy of "Healthy People 2000" (Full
Report:  Stock No. 017-001-00474-0 or Summary Report:  Stock No.
017-001-00473-1) through the Superintendent of Documents, Government
Printing Office, Washington, DC 20402-0325 (telephone 202-512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contacts listed below.

NIAID:
Paolo G. Miotti, M.D., M.P.H.
Telephone:  (301) 496-9176
FAX:  (301) 402-3211
Email:  pm122m@nih.gov

NICHD:
David Burns, M.D., M.P.H.
Telephone:  (301) 496-7339
FAX:  (301) 496-8678
Email:  db98d@nih.gov

NIDA:
Katherine Davenny, Ph.D.
Telephone:  (301) 443-1801
FAX:  (301) 443-2317
Email:  kd25h@nih.gov

NCI:
Sandra Melnick, Dr.P.H.
Telephone:  (301) 435-4914
FAX:  (301) 402-4279
Email:  sm33k@nih.gov

NIDR:
Maryann Redford, D.D.S., M.P.H.
Telephone:  (301) 544-5588
FAX:  (301) 480-8254
Email:  mr48a@nih.gov

NIDDK:
Judith Fradkin, M.D.
Telephone:  (301) 594-8814
FAX:  (301) 480-3503
Email:  jf58s@nih.gov

NINDS:
A.P. Kerza-Kwiatecki, Ph.D.
Telephone:  (301) 496-1431
FAX:  (301) 402-2060
Email:  ak45w@nih.gov

ORWH:
Joyce Rudick
Telephone:  (301) 402-1770
FAX:  (301) 402-1798
Email:  jr27q@nih.gov

$$P1 END ************************************************************