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NIH GUIDE - Vol. 26, No. 29 - August 29, 1997

$$INDEX BEGIN *******************************************************

                               NOTICES

$$INDEX N1 **********************************************************

CHANGE IN RECEIPT DATES FOR NIDA RESEARCH CENTERS GRANT PROGRAM
National Institute on Drug Abuse
INDEX:  DRUG ABUSE

               NOTICES OF AVAILABILITY (RFPs/RFAs/PAs)

$$INDEX R1 01/08/98 *************************************************

ADOLESCENTS AND STDS COOPERATIVE RESEARCH CENTER (RFA AI-97-003)
National Institute of Allergy and Infectious Diseases INDEX:
ALLERGY, INFECTIOUS DISEASES

$$INDEX R2 01/21/98 *************************************************

CENTERS FOR CHILDREN'S ENVIRONMENTAL HEALTH AND DISEASE PREVENTION
RESEARCH (RFA ES-97-004)
National Institute of Environmental Health Sciences
U.S. Environmental Protection Agency, National Center for
Environmental Research and Quality Assurance
INDEX:  ENVIRONMENTAL HEALTH SCIENCES; ENVIRONMENTAL PROTECTION
AGENCY

$$INDEX P1 **********************************************************

AUTOIMMUNITY: GENETICS, MECHANISMS, AND SIGNALING (PA-97-098)
National Institute of Allergy and Infectious Diseases National
Institute of Diabetes and Digestive and Kidney Diseases National
Institute of Arthritis, Musculoskeletal and Skin Diseases National
Institute on Aging
Office of Research on Women's Health
INDEX:  ALLERGY, INFECTIOUS DISEASES; DIABETES, DIGESTIVE, KIDNEY
DISEASES; ARTHRITIS, MUSCULOSKELETAL, SKIN DISEASES; AGING; WOMEN'S
HEALTH

$$INDEX P2 **********************************************************

GENES AND MECHANISMS UNDERLYING PRIMARY IMMUNODEFICIENCY (PA-97-099)
National Institute of Allergy and Infectious Diseases National
Institute of Child Health and Human Development INDEX:  ALLERGY,
INFECTIOUS DISEASES; CHILD HEALTH, HUMAN DEVELOPMENT

$$INDEX P3 **********************************************************

REGULATION OF THE IMMUNE RESPONSE (PA-97-100)
National Institute of Allergy and Infectious Diseases National
Institute on Aging
National Institute of Diabetes and Digestive Diseases and Kidney
Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases
INDEX:  ALLERGY, INFECTIOUS DISEASES; AGING; DIABETES, DIGESTIVE
DISEASES, KIDNEY DISEASES; ARTHRITIS, MUSCULOSKELETAL, SKIN DISEASES

$$INDEX P4 **********************************************************

BASIC MECHANISMS OF VACCINE EFFICACY (PA-97-101)
National Institute of Allergy and Infectious Diseases National
Institute of Dental Research
National Institute on Aging
National Institute of Child Health and Human Development INDEX:
ALLERGY, INFECTIOUS DISEASES; DENTAL RESEARCH; AGING; CHILD HEALTH,
HUMAN DEVELOPMENT

$$INDEX P5 **********************************************************

NINDS CLINICAL TRIAL PLANNING GRANT (PAR-97-102)
National Institute of Neurological Disorders and Stroke INDEX:
NEUROLOGICAL DISORDERS, STROKE

$$INDEX P6 **********************************************************

PILOT CLINICAL TRIAL GRANT FOR NEUROLOGICAL DISEASE (PAR-97-103)
National Institute of Neurological Disorders and Stroke INDEX:
NEUROLOGICAL DISORDERS, STROKE

$$INDEX P7 **********************************************************

CENTERS FOR BEHAVIORAL SCIENCE RESEARCH IN MENTAL HEALTH (PAR-97-104)
National Institute of Mental Health
INDEX:  MENTAL HEALTH

The NIH GUIDE is available electronically via LISTSERV subscription,
and is also on the NIH gopher (gopher.nih.gov) and the NIH website
(http://www.nih.gov). Alternative access is through the NIH Grant
Line via modem (data line 301/402-2221); contact Dr. John James at
301/435-2801 for details on the NIH Grant Line.

All competing grant applications submitted to the National Institutes
of Health must be sent to:

DIVISION OF RESEARCH GRANTS
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)

ASKNIH is a service of the Division of Extramural Outreach &
Information Resources, Office of Extramural Research, Office of the
Director, NIH.  ASKNIH is the point of contact for obtaining general
information about NIH extramural research & research training
programs, requesting publications, and learning more about obtaining
the NIH GUIDE and other information on the NIH web site.  ASKNIH is
also the contact aid which organizations should request application
kits and forms.

ASKNIH
NATIONAL INSTITUTES OF HEALTH
EMAIL:  ASKNIH@odrockm1.od.nih.gov
FAX:  (301) 480-0525
TELEPHONE:  (301) 435-0714

INQUIRIES ABOUT THE NOTICES, PAs, AND RFAs IN THIS PUBLICATION SHOULD
BE DIRECTED TO THE NIH STAFF MEMBER IDENTIFIED AT THE END OF EACH
ITEM.

THE PHS STRONGLY ENCOURAGES ALL GRANT AND CONTRACT RECIPIENTS TO
PROVIDE A SMOKE-FREE WORKPLACE AND PROMOTE THE NON-USE OF ALL TOBACCO
PRODUCTS.  IN ADDITION, PUBLIC LAW 103-227, THE PRO-CHILDREN ACT OF
1994, PROHIBITS SMOKING IN CERTAIN FACILITIES (OR IN SOME CASES, ANY
PORTION OF A FACILITY) IN WHICH REGULAR OR ROUTINE EDUCATION,
LIBRARY, DAY CARE, HEALTH CARE OR EARLY CHILDHOOD DEVELOPMENT
SERVICES ARE PROVIDED TO CHILDREN.  THIS IS CONSISTENT WITH THE PHS
MISSION TO PROTECT AND ADVANCE THE PHYSICAL AND MENTAL HEALTH OF THE
AMERICAN PEOPLE.

$$INDEX END *********************************************************

                               NOTICES

$$N1 BEGIN **********************************************************

CHANGE IN RECEIPT DATES FOR NIDA RESEARCH CENTERS GRANT PROGRAM

NIH Guide, Volume 26, Number 29, August 29, 1997

P.T.

National Institute on Drug Abuse

The National Institute on Drug Abuse (NIDA) wishes to give notice of
a change in the receipt dates for Center grant applications submitted
under NIDA's Research Center Grant Program Guidelines, December 1995.
The previous receipt dates were June 1 and October 1 annually.
Effective immediately, NIDA will accept applications under the NIDA
Research Center Grant Program using the three standard receipt dates
of February 1, June 1, and October 1 (annually).

INQUIRIES

Inquiries regarding this notice may be directed to:

Jacqueline R. Porter
Office of Extramural Program Review
National Institute on Drug Abuse
5600 Fishers Lane, Room 10-42
Rockville, MD  20857
Telephone:  (301) 443-2755
Email:  jp86z@nih.gov

$$N1 END ************************************************************

               NOTICES OF AVAILABILITY (RFPs/RFAs/PAs)

$$R1 BEGIN AI-97-003 FULL-TEXT **************************************

ADOLESCENTS AND STDS COOPERATIVE RESEARCH CENTER

NIH Guide, Volume 26, Number 29, August 29, 1997

RFA AVAILABLE:  AI-97-003

P.T.

National Institute of Allergy and Infectious Diseases

Letter of Intent Receipt Date:  October 15, 1997
Application Receipt Date:  January 8, 1998

PURPOSE

The purpose of this Request for Applications (RFA) is to stimulate
multi-disciplinary, collaborative research to further understanding
of sexually transmitted diseases (STDs) in adolescent populations and
to develop and evaluate effective approaches to their prevention and
control. The Sexually Transmitted Diseases Branch of the Division of
Microbiology and Infectious Diseases (DMID) of the National Institute
of Allergy and Infectious Diseases (NIAID) invites grant applications
for an Adolescents and Sexually Transmitted Diseases Cooperative
Research Center (STD CRC).  The Institute recognizes that adolescents
>From all segments of society are at extremely high risk for STDs.
Furthermore there are unique biomedical and behavioral factors that
underlie the risk of STD acquisition and transmission in adolescents.
Therefore, a research program that specifically focuses on STDs in
this young, at-risk population is likely to be highly productive.
The STD CRC will provide a multi-disciplinary approach to STD
research by bridging biomedical, clinical, behavioral, and
epidemiological research; will foster interaction among STD
investigators; and will facilitate intervention-oriented research.

The estimated total funds (direct and indirect costs) available for
the first year of support for awards under this RFA will be $1.2
million.  In Fiscal Year 1998, the NIAID plans to fund one
Adolescents and STD CRC.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This RFA,
Adolescents and Sexually Transmitted Diseases Cooperative research
Center (STD CRC), is related to the priority areas of STDs & AIDS.
Potential applicants may obtain a copy of "Healthy People 2000" (Full
Report:  Stock No. 017-001-00474-0 or Summary Report:  Stock No.
017-001-00473-1) through the Superintendent of Documents, Government
Printing Office, Washington, DC 20402-0325 (telephone 202-512-1800).

INQUIRIES

The RFA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contact listed below.

Penelope J. Hitchcock
Division of Microbiology and Infectious Diseases
National Institute of Allergy and Infectious Diseases 6003 Executive
Boulevard, Room 3A24
Bethesda, MD  20892
Telephone:  (301) 402-0443
FAX:  (301) 402-1456
Email:  ph22k@nih.gov

$$R1 END ************************************************************

$$R2 BEGIN ES-97-004 FULL-TEXT **************************************

CENTERS FOR CHILDREN'S ENVIRONMENTAL HEALTH AND DISEASE PREVENTION
RESEARCH

NIH Guide, Volume 26, Number 29, August 29, 1997

RFA AVAILABLE:  ES-97-004

P.T.

National Institute of Environmental Health Sciences
U.S. Environmental Protection Agency, National Center for
Environmental Research and Quality Assurance

Letter of Intent Receipt Date:  September 30, 1997
Application Receipt Date:  January 21, 1998

PURPOSE

Establish research/prevention programs addressing environmental
contributions to children's health; facilitate translation into
clinical applications and intervention strategies to reduce the
incidence of environmentally related childhood disease; establish a
network that fosters communication, innovation, and research
excellence with the goal of reducing morbidity among children as a
result of exposure to harmful environmental agents.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This Request
for Applications (RFA), Specialized Centers in Children's
Environmental Health, is related to the priority area of
Environmental Health. Potential applicants may obtain a copy of
"Healthy People 2000" (Full Report:  Stock No. 017-001-00474-0 or
Summary Report: Stock No. 017-001-00473-1) through the Superintendent
of Documents, Government Printing Office, Washington, DC 20402-9325
(telephone 202-512-1800).

INQUIRIES

The RFA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contact listed below.

Allen Dearry, Ph.D.
Division of Extramural Research and Training
National Institute of Environmental Health Sciences
P.O. Box 12233, EC-21
Research Triangle Park, NC  27709
Telephone:  (919) 541-4500
FAX:  (919) 541-4937
Email:  dearry@niehs.nih.gov

Christopher Saint, Ph.D.
National Center for Environmental Research and Quality Assurance U.S.
Environmental Protection Agency
401 M Street, SW (8723R)
Washington, DC  20460
Telephone:  (202) 564-6909
FAX:  (202) 565-2448
Email:  saint.chris@epamail.epa.gov

$$R2 END ************************************************************

$$P1 BEGIN PA-97-098 FULL-TEXT **************************************

AUTOIMMUNITY: GENETICS, MECHANISMS, AND SIGNALING

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PA-97-098

P.T.

National Institute of Allergy and Infectious Diseases National
Institute of Diabetes and Digestive and Kidney Diseases National
Institute of Arthritis, Musculoskeletal and Skin Diseases National
Institute on Aging
Office of Research on Women's Health

PURPOSE

The National Institute of Allergy and Infectious Diseases (NIAID),
National Institute of Diabetes and Digestive and Kidney Diseases
(NIDDK), National Institute of Arthritis, Musculoskeletal and Skin
Diseases (NIAMS), National Institute on Aging (NIA), and the Office
of Research on Women's Health, National Institutes of Health (NIH)
invite applications for new and innovative investigator-initiated
basic and preclinical research into the immune responses underlying
autoimmune disease and its regulation for preventive or therapeutic
purposes.  Three specific areas of emphasis are highlighted:  1)
genetic susceptibility for autoimmune disease, including the MHC and
other genetic loci;  2) role and regulation of co-stimulation of T
cells in autoimmunity; and 3) signal transduction in the autoreactive
response.  The funding mechanisms to be used to support research
under this PA are research project grants (R01) and First Independent
Research Support and Transition (FIRST) (R29) awards.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This PA,
Autoimmunity: Genetics, Mechanisms, and Signaling, related to the
priority area of Diabetes and Chronic Disabling Diseases. Potential
applicants may obtain a copy of "Healthy People 2000" (Full Report:
Stock No. 017-001-00474-0 or Summary Report:  Stock No.
017-001-00473-1) through the Superintendent of Documents, Government
Printing Office, Washington, DC 20402-9325 (telephone 202-512-1800).

INQUIRIES

This PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221, the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov)), and by mail and email from the
program contact listed below.

Elaine Collier, M.D.
Division of Allergy, Immunology and Transplantation
National Institute of Allergy and Infectious Diseases 6003 Executive
Boulevard, Room 4A20 - MSC 7640
Bethesda, MD  20892-7640
Telephone:  (301) 496-7104
FAX:  (301) 402-2571
Email:  ec5x@nih.gov

$$P1 END ************************************************************

$$P2 BEGIN PA-97-099 FULL-TEXT **************************************

GENES AND MECHANISMS UNDERLYING PRIMARY IMMUNODEFICIENCY

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PA-97-099

P.T.

National Institute of Allergy and Infectious Diseases National
Institute of Child Health and Human Development

PURPOSE

The National Institute of Allergy and Infectious Diseases (NIAID) and
the National Institute of Child Health and Human Development (NICHD),
National Institutes of Health (NIH), invite applications for research
studies to:  identify and characterize genes that cause primary
immunodeficiency diseases; characterize the molecular mechanisms
involved in primary immunodeficiency diseases which are not the
result of a single defective gene; identify the immunologic role of
defective gene products and their normal counterparts; and, based on
this knowledge, develop more effective approaches for the diagnosis,
treatment, and prevention of these disorders.  The funding mechanisms
to be used to support research under this PA are R01s and R29s.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This Program
Announcement, "GENES AND MECHANISMS UNDERLYING PRIMARY
IMMUNODEFICIENCY", is related to the priority areas of Maternal and
Infant Health and Diabetes and Chronic Disabling Diseases.  Potential
applicants may obtain a copy of "Healthy People 2000" (Full Report:
Stock No. 017-001-00474-0 or Summary Report:  Stock No.
017-001-00473-1) through the Superintendent of Documents, Government
Printing Office, Washington, DC 20402-9325 (telephone 202-512-1800).

INQUIRIES

This PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221, the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov)), and by mail and email from the
program contact listed below.

Howard B. Dickler, M.D.
Division of Allergy, Immunology, and Transplantation National
Institute of Allergy and Infectious Diseases 6003 Executive
Boulevard, Room 4A-19
Bethesda, MD  20892-7640
Telephone:  (301) 496-7104
FAX:  (301) 402-2571
Email:  hd7e@nih.gov

$$P2 END ************************************************************

$$P3 BEGIN PA-97-100 FULL-TEXT **************************************

REGULATION OF THE IMMUNE RESPONSE

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PA-97-100

P.T.

National Institute of Allergy and Infectious Diseases National
Institute on Aging
National Institute of Diabetes and Digestive Diseases and Kidney
Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases

PURPOSE

The National Institute of Allergy and Infectious Diseases (NIAID),
the National Institute on Aging (NIA), the National Institute of
Diabetes and Digestive and Kidney Diseases (NIDDK), and the National
Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS),
National Institutes of Health (NIH), invite applications to enhance
our knowledge of the broad range of mechanisms that control the
immune response and age-related changes in the regulation of immune
responses and the underlying mechanisms responsible for these
changes.  Enhanced knowledge in these areas is critical for
understanding the generation and control of immune responses to
antigenic challenges and in the development of new strategies to
treat and prevent immunologically based diseases.  Support will be
provided for basic and pre-clinical studies using molecular and
cellular approaches to dissect the immune response.  The funding
mechanisms to be used to support research under this Program
Announcement (PA) are R01s and R29s.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This PA,
"REGULATION OF THE IMMUNE RESPONSE", is related to the priority areas
of Immunization and Infectious Diseases and Diabetes and Chronic
Disabling Disease.  Potential applicants may obtain a copy of
"Healthy People 2000" (Full Report:  Stock No. 017-001-00474-0 or
Summary Report:  Stock No. 017-001-00473-1) through the
Superintendent of Documents, Government Printing Office, Washington,
DC 20402-9325 (telephone 202-512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contact listed below.

Stephen M. Rose, Ph.D.
Division of Allergy, Immunology and Transplantation
National Institute of Allergy and Infectious Diseases 6003 Executive
Boulevard, Room 4A14
Bethesda, MD  20892-7640
Telephone:  (301) 496-5598
FAX:  (301) 402-2571
Email:  sr8j@nih.gov

$$P3 END ************************************************************

$$P4 BEGIN PA-97-101 FULL-TEXT **************************************

BASIC MECHANISMS OF VACCINE EFFICACY

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PA-97-101

P.T.

National Institute of Allergy and Infectious Diseases National
Institute of Dental Research
National Institute on Aging
National Institute of Child Health and Human Development

PURPOSE

The National Institute of Allergy and Infectious Diseases (NIAID),
the National Institute of Dental Research (NIDR), the National
Institute on Aging (NIA), and the National Institute of Child Health
and Human Development, National Institutes of Health (NIH), invite
applications that utilize basic knowledge of antigen presentation
pathways, lymphocyte activation and immunoregulation to define
fundamental principles of vaccine efficacy. Innovative studies are
sought to develop vaccination strategies applicable for broad classes
of pathogens or to define approaches to direct specific immune
responses in order to enhance vaccine effectiveness for infectious
pathogens.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This Program
Announcement (PA), BASIC MECHANISMS OF VACCINE EFFICACY, is related
to the priority areas of Immunization and Infectious Diseases, HIV
Infection and Maternal and Infant Health.  Potential applicants may
obtain a copy of "Healthy People 2000" (Full Report: Stock No.
017-001-00474-0 or Summary Report: Stock No. 017-001-00473) through
the Superintendent of Documents, Government Printing Office,
Washington, DC 20402-9325 (telephone 202-512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
program, may be obtained electronically through the NIH Grant Line,
(data line 301-402-2221) and the NIH Gopher (gopher@nih.gov) and the
NIH Website (Http://www.nih.gov) and by mail and Email from the
program contacts listed below.

Charles Hackett, Ph.D.
Division of Allergy, Immunology and Transplantation
National Institute of Allergy and Infectious Diseases 6003 Executive
Boulevard, Room 4A23
Bethesda, MD  20892-7640
Telephone:  (301) 496-7551
FAX:  (301) 402-2571
Email:  ch187q@nih.gov

Dennis F. Mangan, Ph.D.
Division of Extramural Research
National Institute of Dental Research
Building 45, Room 4AN-32F
Bethesda, MD  20892-6402
Telephone:  (301) 594-2421
FAX:  (301)480-8318
Email:  Dennis.Mangan@nih.gov

Anna McCormick, Ph.D.
Biology of Aging Program
National Institute on Aging
Gateway Building, Suite 2C231
Bethesda, MD  20892
Telephone:  (301) 496-6402
FAX:  (301) 402-0010
Email:  am38k@nih.gov

Allen Lock, D.V.M.
Center for Research for Mothers and Children
National Institute for Child Health and Human Development 6100
Executive Boulevard, Room 4B01 - MSC-7510
Bethesda, MD  20892-7510
Telephone:  (301) 496-5541
FAX:  (301) 402-4083
Email:  locka@hd01.nichd.nih.gov

$$P4 END ************************************************************

$$P5 BEGIN PAR-97-102 FULL-TEXT *************************************

NINDS CLINICAL TRIAL PLANNING GRANT

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PAR-97-102

P.T.

National Institute of Neurological Disorders and Stroke

PURPOSE

The National Institute of Neurological Disorders and Stroke (NINDS)
seeks to fund high quality clinical trials to evaluate treatments for
neurological disorders.  The NINDS Clinical Trial Planning Grant
allows for early peer review of the rationale and design for clinical
trials of treatments for neurological disorders and provides support
for the development of a detailed clinical trial research plan,
including a complete manual of operations and procedures.  The
mechanism of support will be a Developmental Planning Grant (R21),
which will provide up to $150,000 in direct costs for a single year.
The award cannot be renewed.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This PA,
Title of PA, is related to the priority area of chronic disabling
conditions.  Potential applicants may obtain a copy of "Healthy
People 2000" (Full Report:  Stock No. 017-001-00474-0 or Summary
Report:  Stock No. 017-001-00473-1) through the Superintendent of
Documents, Government Printing Office, Washington, DC 20402-9325
(telephone 202-512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contact listed below.

Joseph S. Drage, M.D.
Training and Special Programs Officer,
National Institute of Neurological Disorders and Stroke Telephone:
(301) 496-4188
FAX:  301-402-0302
Email:  jd66x@nih.gov

$$P5 END ************************************************************

$$P6 BEGIN PAR-97-103 FULL-TEXT *************************************

PILOT CLINICAL TRIAL GRANT FOR NEUROLOGICAL DISEASE

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PAR-97-103

P.T.

National Institute of Neurological Disorders and Stroke

PURPOSE

The National Institute of Neurological Disorders and Stroke (NINDS)
is committed to identifying effective treatments for neurological
disorders by supporting well-executed clinical trials.  Before
proceeding to a full-scale clinical trial, pilot clinical studies are
often required.  The NINDS announces its interest in supporting pilot
studies required to obtain necessary information to clearly establish
the clinical basis for proceeding to a full-scale trial.  The purpose
of the NINDS Pilot Clinical Trial Grant For Neurological Disease is
to obtain preliminary data and conduct studies to support the
rationale for a subsequent full-scale clinical trial of an
intervention to treat or prevent neurological disease.  The mechanism
of support for the NINDS Pilot Clinical Trial Grant is the research
project grant (R01).  It is expected that most grants will not exceed
$350,000 per year in direct costs for three years.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This PA,
Title of PA, is related to the priority area of chronic disabling
conditions.  Potential applicants may obtain a copy of "Healthy
People 2000" (Full Report:  Stock No. 017-001-00474-0 or Summary
Report:  Stock No. 017-001-00473-1) through the Superintendent of
Documents, Government Printing Office, Washington, DC 20402-9325
(telephone 202- 512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations, and award criteria for this
solicitation, may be obtained electronically through the NIH Grant
Line (data line 301/402-2221), the NIH GOPHER (gopher.nih.gov), and
the NIH Website (http://www.nih.gov), and by mail and email from the
program contact listed below.

Joseph S. Drage, M.D.
Training and Special Programs Officer,
National Institute of Neurological Disorders and Stroke Telephone:
(301) 496-4188
FAX:  301-402-0302
Email:  jd66x@nih.gov

$$P6 END ************************************************************

$$P7 BEGIN PAR-97-104 FULL-TEXT *************************************

CENTERS FOR BEHAVIORAL SCIENCE RESEARCH IN MENTAL HEALTH

NIH Guide, Volume 26, Number 29, August 29, 1997

PA AVAILABLE:  PAR-97-104

P.T.

National Institute of Mental Health

PURPOSE

The National Institute of Mental Health (NIMH) invites centers grant
(P50) applications for Centers for Behavioral Science Research in
Mental Health (CBSR).  The purpose of these Centers is to provide
integrated multidisciplinary research environments in which to pursue
focused questions in basic behavioral science related to mental
health and mental disorder.  This mechanism is intended to encourage
investigators from a variety of disciplines and approaches to
contribute the full range of expertise and advanced technologies
available in basic behavioral science toward the understanding of
mechanisms underlying mental health and mental illness, and to begin
the translation of basic behavioral findings and techniques to
relevant clinical issues.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas.  This Program
Announcement (PA), Centers for Behavioral Science Research in Mental
Health, is related to the priority area of mental health and mental
disorders.  Potential applicants may obtain a copy of "Healthy People
2000" (Full Report:  Stock No. 017-001-00474-0 or Summary Report:
Stock No. 017-001-00473-1) through the Superintendent of Documents,
Government Printing Office, Washington, DC 20402-9325 (telephone
202-512-1800).

INQUIRIES

The PA, which describes the research objectives, application
procedures, review considerations and award criteria for this
program, may be obtained electronically through the NIH Grant Line
(data line 301-402-2221) and the NIH Home Page (www.nih.gov) and by
mail and E-mail from the program contact listed below.

Mary Ellen Oliveri, Ph.D.
Division of Mental Disorders, Behavioral Research, and AIDS National
Institute of Mental Health
5600 Fishers Lane, Room 18C-26
Rockville, MD  20857
Telephone:  (301) 443-3942
FAX:  (301) 443-4822
Email:  MOLIVERI@NIH.GOV

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