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Article #12new gene ontology software
From: Bernard
Date: Mon, 28 Feb 2005 13:38
Date: Mon, 28 Feb 2005 13:38
55 lines
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3750 bytes
Dear colleagues, This short mail to inform the community of people interested in the development and use of new WWW resources for biologists of the availability of GOToolBox, a series of programs using Gene ontology that we published recently in Genome biology (http://www.biomedcentral.com/content/pdf/gb-2004-5-12-r101.pdf). The programs from GOToolBox are directly accessible through a Web site described in the article. They can be useful to analyse groups of genes derived from microarrays,Chromatin-Immunoprecipitations, from the analysis of protein-protein, protein_DNA and/or genetic networks, .... They ca therefore be of potential utility for functional annotations of chromosomes. GOToolBox performs five main tasks: - gene dataset creation, - selection and fitting of GO terms at a given ontology level (GO-Diet), - statistical analysis of GO terms associated with gene sets (GO-Stats) in order to find over- or under-represented terms, - GO-based gene clustering (GO-Proxy) allowing to find sub-groups of functionnally related genes within a gene set, - gene retrieval based on GO annotation similarity (GO-Family) in one or several species. Other developments are presently on their way. At the moment, GOToolBox supports analyses of GO terms for six species : Yeast (Sc), Arabidopsis, Drosophila, nematode, mouse and humans. For the authors, David Martin and Bernard Jacq Bernard Jacq LGPD-IBDM Parc Scientifique de luminy 13288 Marseille Cedex 9 tel (33) 04 91 82 94 25 fax (33) 04 91 82 06 82 Nous sauverons la recherche: Signez et faites signer l'appel pour une loi de la recherche conforme � l'esprit des EGR de Grenoble http://recherche-en-danger.apinc.org/ ---
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From: jacq@ibdm.univ-mrs.fr (Bernard)
Newsgroups: bionet.software.www
Subject: new gene ontology software
Date: 28 Feb 2005 13:38:32 -0000
Organization: BIOSCI/MRC Rosalind Franklin Centre for Genomics Research
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