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Article #2221

Exon Mapping

#2221
From: Iddo Friedberg
Date: Thu, 26 Jun 1997 00:00
41 lines
1543 bytes
Hi,

I'm looking for an elegant (failing that, feasable) method to map
genomic sequences to
protein sequences. The net result should look something like this:

Genomic: -------++++++-----------+++++++++++-----++++++
Protein:        ******           ***********     ******

Where the "+" are exon codons, "-" intron codons, and "*" amino-acids.

Naturally, the data can appear as a mapping table, or anything else
which is parseable.

Given protein sequence (e.g. from SwissProt), how do I:

1) Trace the genomic sequence? Problem: usually I cannot find it, rather
I come up with a cDNA. I do not actually need the intron information,
but I do need to know where an exon begins and ends on the cDNA
sequence.

2) Map the above information to my protein sequence.

I have GCG v9.0, and WWW access. My platform is a Silicon-Graphics Indy.

Any comment would be useful.

Many thanks,

Iddo




-- 
Iddo Friedberg
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email: idoerg@cc.huji.ac.il
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From: Iddo Friedberg <idoerg@cc.huji.ac.il>
Subject: Exon Mapping
Date: 1997/06/26
Message-ID: <33B26438.3F54@cc.huji.ac.il>
X-Deja-AN: 252707953
Organization: The Hebrew University of Jerusalem
Newsgroups: bionet.software,bionet.software.gcg