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5th National Symposium cum Workshop on �Recent Trends in Structural Bioinformatics and Computer Aided Drug Design� [SBCADD�2013]
19th- 22rd February, 2013
Organized by
Department of Bioinformatics
ALAGAPPA UNIVERSITY
(Reaccredited with �A� Grade by NAAC )
KARAIKUDI � 630003, TAMIL NADU, INDIA

SYMPOSIUM THEME
Human Genome Project is largely complete, so the problem facing by scientists is how to maximize the use of the newly acquired data for improving health care. It is estimated that the number of therapeutic targets available for drug discovery will increase from the current number of 600 to 1000 to perhaps as many as 5000 to 10,000. In addition to the challenges that this number provides to the pharmaceutical industry, there is the issue of sequence variation through Single Nucleotide Polymorphisms (SNPs), some of which may impact upon the way that the body handles drug treatment. This may be due to a direct effect on the binding site of the protein target through non-conservative alterations of the amino acid sequence, or else through indirect effects on drug metabolizing enzymes. In order to meet these challenges, the combination of structural proteomics and computer-aided small molecule design provides opportunities for creating new molecules in silico; these may be designed to bind to selected pharmacogenetic variants of a protein in order to overcome the non-responsiveness of certain patient groups to a particular medicine. 
In silico drug discovery methods reduce both time and cost of development of novel drug/lead molecules. Knowledge about the molecule, its interaction with the drug, molecular modeling, and new drug development creates an awareness of the molecule at the organ level and aids in the prevention, diagnosis, and treatment of diseases. Computational tools have the advantage of delivering new lead candidates more quickly and at lower cost. In the 21st century, in silico methods facilitate target identification, structure prediction and lead/drug discovery. The computational methods expect more reliable and expeditious protocols for development of novel ideas, which increase the potential leads. The computer-assisted molecular design has succeeded in the QSAR and protein modeling algorithms to improve activity of lead compounds. Selecting candidates via the described in silico virtual screening, should help to reduce the list of candidate molecules and thereby reduce time and costs significantly.

LIST OF SPEAKERS (TENTATIVE)
Dr. M.R.N. Murthy, Indian Institute of Science, Bangalore
Dr. D. Velmurugan, University of Madras, Chennai 
Dr. P. Gautham, Anna University, Chennai 
Dr. Mukesh Doble, Indian Institute of Technology (IIT) Madras
Dr. D. Sundar, Indian Institute of Technology (IIT), Delhi 
Dr. Basant Kumar Tiwary, Pondicherry University, Pudhucherry
Dr. R. Raghu, Schrodinger GmbH, USA 

PARTICIPANTS
Students, Research Scholars, Research Scientists and Faculty members from the Universities, Colleges, Institutes and Industries.
Call for Poster Presentation:All the participants are invited to submit an abstract of one page in English, describing their original research related to the theme of this symposium cum workshop. The abstract must be sent to dbiconf@gmail.com. Kindly visit the conference website for more details.

SCIENTIFIC TOPICS
Small and Macromolecule X-ray Crystallography 
Protein Modeling and Molecular Docking 
Molecular Mechanics & Dynamics 
Pharmacophore Modeling & 3D-QSAR 
Free Energy Calculation Methods 
De Novo Drug Design 
Quantum Chemistry 
Functional Genomics and Proteomics 
Pharmacogenomics 
Database Creation and Development 
Text and Data mining 

REGISTRATION
The participants are requested to send the filled in registration form along with registration fee on or before February 1st, 2013. The DD should be drawn in favour of Organizing Secretary, payable at Karaikudi.
Students                                                                          : Rs. 750
 Research Scholars                                                          : Rs. 1000
 Faculties from Academic Institution                              : Rs. 1500
 Faculties from Non Academic Institution / Industries   : Rs. 2000

ACCOMMODATION
Request for accommodation should be sent to the organizing secretary at the earliest opportunity to the students in the University Hostel/Hotel. The expenses for accommodation and food will be met by the participants.
Please log on to http://conf.bioinfoau.org/sbcadd'2013/index.html  for more details

ADDRESS FOR COMMUNICATION
Dr. P. Srinivasan
Organizing Secretary, SBCADD� 2013
Department of Bioinformatics
Science Block, 4th Floor
Alagappa University, Karaikudi - 630 004
Tamil Nadu, India.
Phone     : + 91 - 4565 230725
Fax         : + 91 - 4565 225202
Mobile   : + 91 - 9444482814
Mail       : dbiconf@gmail.com
Web       : http://conf.bioinfoau.org/sbcadd'2013/index.html