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Here's the detail on using Winword 6 with EndNote Plus:

We do not now have a Winword 6 formatter, not is it likely that it will 
be included in the DOS version of the program; it will be included in our 
Windows version.  Winword 6 is an OLE 2 application.  That means that a 
Winword 6 file may contain embedded or linked information from any number 
of different sources. In order to reliably access the information in the 
file, we must use the OLE 2 API, which is only available to a Windows 
application.  We have considered building a small VxD driver to 
communicate with DOS EndNote for this purpose, but have decided to focus 
our resources on the full Windows version of the program, rather than 
this sort of interim fix.

To format a Winword 6 document with the current version of EndNote Plus, 
you will have to save the document as either a Rich Text Format (RTF) or 
Winword 2 document. Neither format is ideal, as you will lose any links 
contained in the file. You must also be careful not to overwrite the RTF 
or Winword 2 copy of the file with the Winword 6 version.  When you close 
Winword, it will ask you if you want to save changes; if you do, and if 
you do not specify a new file name, Winword will save the file in version 
6 format using the last file name used.

A few observations (and opinions) on Winword 6:

Personally, I have found Winword 6 to be slower and less reliable than 
Winword 2, so I would caution against upgrading to the new version 
without good reason.

If you do upgrade, make sure that you obtain the 6.0a interim upgrade 
version, or that you use Windows for Workgroups 3.11.  Both of these 
include VSHARE.386, a virtual device driver that replaces SHARE.EXE.  
VSHARE allocates file locks dynamically, and doesn't use any DOS memory. 
This makes both Winword and EndNote work better.  You should also heed 
Microsoft's warning about setting the FILES parameter in CONFIG.SYS to at 
least 50.

Finally, if you have Microsoft's VSAFE virus checker resident, you may 
start getting false "sharing violations" in EndNote after you install 
Winword 6.  You can disable VSAFE or mark ENPLUS.EXE as read-only to 
avoid these warnings.  Do not try to remove SHARE or VSHARE, as Winword 6 
will not run without them.

Noah Jacobs
EndNote Technical Support