Article View: sci.bio
Article #2841Re: MRNA
From: Ken Easlon
Date: Sun, 10 Jan 1993 01:49
Date: Sun, 10 Jan 1993 01:49
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2835 bytes
In article <103684@netnews.upenn.edu> , rowe@pender.ee.upenn.edu (Mickey Rowe) writes: >So where are you headed with this? A few weeks ago I made a wild statement in another news group (comp.ai.philosophy) that the brain might well be the dumbest organ in the body. This idea was based on the concept that cells-as-computers can be seen as more than an analogy or metaphor, that cells actually perform in ways that are very similar to other digitally controlled systems, under the direction of DNA. The brain statement is based on the fact that neurons have less DNA per unit weight than other kinds of cells (eggs-cluding eggs and who knows what other special cases). Neurons which survive just keep growing and branching, adding an additional burden on the existing nucleus. If cellular smarts is important to the survival of the organism, then one kind of brain smarts diminishes with age. Of course the synaptic organization type of smarts continues to develop with age, up to a point, and I'm sure it adds more survivability to the organism than is lost in DNA power. Anyway, the dumb brain statement was meant as a joke, but in the process of defending the argument I developed the need to know a few molecular biological basics such as the rate at which the nucleus issues instructions to the cellular machinery. If we take Sean Eddy's estimate of the mRNA data rate of 200 kilobytes per second per cell (article <eddy.725706161@beagle>), and if we figure one codon triplet equals one computer type instruction, then I get 3 x 10^5 instructions per second per cell. With the human body's cell count at 10^14 (plus or minus), that comes to about 3 x 10^19 cellular instructions per second. At 100 billion neurons per human nervous system, the cellular computing power would be about 3 x 10^16 or about .1% of the body's total cellular computing power. Not terribly impressive since the nervous system probably accounts for about 2% of the body weight (That's using the familiar 3 lb quote in the popular literature, I don't know what percentage is glial cells). By comparison, Hans Moravec estimates brain (synaptic) power at 1 x 10^13 computations per second, but of course that's apples and oranges. Anyway, thanks to everyone who responded. -- Ken Easlon | "...somebody spoke and I went into a dream..." ken@holonet.net | -Paul McCartney Pleasantly Unaffiliated |
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Newsgroups: sci.bio Path: arc1-ca.pugleaf.net!sparky!uunet!gatech!usenet.ins.cwru.edu!agate!iat.holonet.net!ken From: ken@iat.holonet.net (Ken Easlon) Subject: Re: MRNA Message-ID: <C0M7pv.2B1@iat.holonet.net> Organization: HoloNet National Internet Access BBS: 510-704-1058/modem References: <103684@netnews.upenn.edu> Date: Sun, 10 Jan 1993 01:49:06 GMT Lines: 54