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Article #4255

Re: embryology. A mini tutorial

#4255
From: Sue Miller
Date: Sun, 23 Apr 1989 22:24
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In article <1957@trantor.harris-atd.com> hnewstrom@x102a.harris-atd.com (Harvey Newstrom) writes:
>
>In humans the Y chromosome produces males, while its lack produces females.
>Thus, XXY is male, while XXX is female.  XO is female, but I don't think any
>survive in humans.

   XO is female, but they do survive in humans - the resulting abnormal
condition is called Turner's syndrome.  The phenotypic characteristics
of Turner's syndrome are short stature, wide, web-like neck, poorly developed
breasts, and immature internal sexual organs, and sometimes mental deficiency.
I used to work with a woman whose daughter-in-law had Turner's syndrome -
she was short, but not really "abnormal" in appearance (whatever that means).

   What surprises me a little is that many organisms are pretty tolerant
about wide ranging variations in number/distribution of the sex chromosomes,
but such variations are definitely NOT tolerated well in the autosomal
pairs.  Trisomy-21, familiar to all as Down syndrome, is the only common
such aberration, and it involves a fair amt of impairment (depending on the
individual, of course).  My genetics textbook lists 2 other trisomic
abnormalities, trisomy-13 (1/5000 births) and trisomy-18 (1/10000 births).
It's my understanding that these 2 conditions have extremely high mortality
rates, and surviving victims are quite severely handicapped.  

   Warning - WAG follows:  Can it be that there isn't such a big deal about
our sex after all?  :-)
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
  Sue Miller         {decvax,hplabs,amdahl,nsc}!sun!sunburn!gtx!sue
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 
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References: <3229@imagen.UUCP> <UYBJL6y00Xc4Q2l1If@andrew.cmu.edu> <Apr.1.21.19.41.1989.4147@topaz.rutgers.edu> <169@ascom.UUCP> <1957@trantor.harris-atd.com>

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Path: arc1-ca.pugleaf.net!utzoo!utgpu!jarvis.csri.toronto.edu!mailrus!ames!ncar!noao!asuvax!hrc!gtx!sue
From: sue@gtx.com (Sue Miller)
Newsgroups: sci.bio
Subject: Re: embryology. A mini tutorial
Message-ID: <965@gtx.com>
Date: 23 Apr 89 22:24:13 GMT
References: <3229@imagen.UUCP> <UYBJL6y00Xc4Q2l1If@andrew.cmu.edu> <Apr.1.21.19.41.1989.4147@topaz.rutgers.edu> <169@ascom.UUCP> <1957@trantor.harris-atd.com>
Reply-To: sue@gtx.UUCP (Sue Miller)
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