🚀 go-pugleaf

Per my comments on DMSO in terms of carcinogenesis, teratogenesis, etc.:

Perhaps I should have been more specific.  It is possible that any such
activity attributed to DMSO is a function of the compounds ability to act
as a carrier for almost anything.  In many instances, substances that
can't be solubilized in aqueous media are readily soluble in DMSO.  It is
a fantastic vehicle for solubilization.  In part, that is the problem. As
such any potentially carcinogenic agent is readily delivered by DMSO.

However, it is also very likely that DMSO may indeed have carcinogenic
properties.  In biological systems, DMSO is used as a lipid/membrane
modifying agent.  It will easily alter membrane function, protein
distribution, etc.  As such, it is not surprising that the agent could
cause genetic alterations at the cellular level (ie. via nuclear membrane
modification).  Also, it should be noted that in experimental settings,
DMSO is actually used *because* of it's ability to transform cells, for
example, as a differentiating agent for myeloblastoid cell types (U937
cell lines) to force polymorphonuclear leukocyte-like cell type formation.

In essence, some of the commentary I've heard is that DMSO is currently
considered much as compounds like acetone used to be.....no real hazard. 
The reality has become somewhat different.

Cheers,

Marc

--
Dr. Marc Wiles
George Washington University Medical Center