how do you look for downstream genes (Homeobox example)

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1 total messages Started by Michael Levin Wed, 23 Dec 1992 15:03

#2564

Author: Michael Levin
Date: Wed, 23 Dec 1992 15:03

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   We were studying the role of homeobox genes in the chick limb (in a
class on developmental biology). It appears that different hox genes
get turned on in different parts of the limb, forming a position-code.
I am interested in how, once these genes turn on (read the positional
information), they then cause the proper morphological development of
the limb. So, does anyone know anything about the down-stream effects
of Hox genes? If so, are there references? How would one go about
studying this? In general, how does one look for downstream effects of
genes? Please reply to mlevin@husc8.harvard.edu.


Mike Levin

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