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In Article<314F2374.2727@dundee.ac.uk>, <a.treumann@dundee.ac.uk> write:
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> Newsgroups: bionet.molbio.methds-reagnts,bionet.molbio.proteins,sci.chem
> Subject: Acetylcholinesterase (AChE) regeneration after DFP?
> Message-ID: <314F2374.2727@dundee.ac.uk>
> From: Achim Treumann <a.treumann@dundee.ac.uk>
> Date: Tue, 19 Mar 1996 13:13:24 -0800
> Organization: Dept. of Biochemistry, Univ. of Dundee
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> 
> Dear netters, 
> 
> Acetylcholinesterase (AChE) can be inhibited with 
> diisopropylfluorophosphate (DFP). Howver, the inhibited enzyme can be 
> reactivated with oximes or hydroxamic acid derivatives. In our lab we 
> would like to reactivate a different (parasitic) esterase, which has been 
> inhibited with DFP. However, most of the reactivators described in the 
> literature do not seem to be available from the usual suppliers. 
> 
> Can anybody point us to any of the following compounds (commercial 
> availability, a kind gift or an easy synthetic approach):
> 
> - P2S (1-methyl-2-hydroxyiminomethylpyridinium methane sulfonate)
> - hydroxyiminoacetone
> - N-phenylnicotinohydroxamic acid
> - formhydroxamic acid
> 
> Please send an email to Dundee and/or answer to this newsgroup. 
> 
> Ta, 
> Achim
> 
> -- 
> Achim Treumann
> Dept. Biochemistry			Tel. +44-1382-344301
> University of Dundee			fax  +44-1382-322583
> Dundee DD1 4HN				
> Scotland, UK			email a.treumann@dundee.ac.uk
If you contact SIGMA Chemical, they have a fast turnover on new compounds and 
wellcome the suggestions.  Give them the formula and they will produce it.