Article View: sci.chem
Article #2360Re: What is TTX?
From: Ishai Rabinovitz
Date: Tue, 22 Sep 1998 00:00
Date: Tue, 22 Sep 1998 00:00
29 lines
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2154 bytes
and its cheap too ! just 98.00$ per gram.... classified9588@my-dejanews.com wrote: > TTX, Tetrodotoxin, is a sodium channel blocker. It binds to the receptors of > sodium channels preventing them to allow passage of sodium ions through a > membrane. > > Why it is a toxin, is that it is poisonous and will kill a human at certain > levels. The toxic mechanism of action is the blocking of sodium channels, > usually voltage gated, and the subsequent loss of an action potential which > would be required to release calcium in a muscle cell-for example. Thus the > muscle is unable to contract or enters in a state of tetany. > > The allure of the blowfish, when properly prepared, gives one the tingling > sensation upon tasting the meat. Of course, this is at low levels; hopefully > if you want to walk away from your meal. > > TTX poisoning is generally treated by artificial respiration and subsequent > connection of the patient to a ventilator. TTX works very similar to STX, or > Saxitoxin which is from clams and mussels who feed during a red tide. > > Not all sodium channel blockers are bad. Most local anesthetics are sodium > channel blockers which will work on Type iii-iV pain receptors, blocking > their depolarization and allowing the doc or dentist to work without you > feeling every nick, prick, and cut. > > -----== Posted via Deja News, The Leader in Internet Discussion ==----- > http://www.dejanews.com/rg_mkgrp.xp Create Your Own Free Member Forum
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X-Google-Language: ENGLISH,ASCII-7-bit X-Google-Thread: f4886,468a7313c825fb5b X-Google-Attributes: gidf4886,public X-Google-Thread: 103efd,468a7313c825fb5b X-Google-Attributes: gid103efd,public From: Ishai Rabinovitz <ishai_r@netvision.net.il> Subject: Re: What is TTX? Date: 1998/09/22 Message-ID: <3606E992.541E8BBA@netvision.net.il> X-Deja-AN: 393479525 Content-Transfer-Encoding: 7bit References: <35E19DDA.DB6970A5@erols.com> <35E44846.4220FBCB@tconl.com> <6t040u$4fq$1@nnrp1.dejanews.com> Content-Type: text/plain; charset=us-ascii Organization: NetVision LTD. Mime-Version: 1.0 Newsgroups: sci.chem,bionet.toxicology