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3 messages
3 total messages Started by Doug Skrecky Mon, 24 Jan 2000 00:00
possible biostasis with rooibos tea?
#361
Author: Doug Skrecky
Date: Mon, 24 Jan 2000 00:00
64 lines
4368 bytes
Citations: 1-2
<1>
Authors
  Lamosova D.  Jurani M.  Greksak M.  Nakano M.  Vanekova M.
Institution
  Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences,
  Ivanka pri Dunaji, Slovakia. LAMOSOVA@UBGZ.SAVBA.SK
Title
  Effect of Rooibos tea (Aspalathus linearis) on chick
  skeletal muscle cell growth in culture.
Source
  Comparative Biochemistry & Physiology. Part C Pharmacology, Toxicology,
  Endocrinology.  116(1):39-45, 1997 Jan.
Abstract
  Rooibos tea (RT) extract contains natural antioxidants and
  scavenging agents. We investigated the effects of different concentrations of
  RT extract in medium on growth and changes of growth parameters of cultured
  chick embryonic skeletal muscle cells. Presence of 2, 10 and 100% of RT
  extract in the culture of primary cells significantly inhibited cell
  proliferation. The inhibition of cell growth reflected on decreased DNA, RNA
  and protein contents in primary cell culture and fibroblasts and myoblasts.
  The ability of the primary cells, fibroblasts and myoblasts to synthesize DNA
  and protein in the presence of RT extract, measured as an amount of
  [3H]thymidine and [3H]leucine incorporated into DNA and de novo synthesized
  protein, corresponded with decreasing DNA and protein contents in all three
  cell types. The inhibition effect of RT rose with increasing concentration of
  the tea extract in the culture medium. Ornithine decarboxylase activity was
  significantly affected only by 100% RT extract in every examined cell types.
  These results suggest that the inhibitory effect of RT extract on the growth
  of primary cells, fibroblasts and myoblasts is due to the potent scavenging
  activity of the RT extract.

<2>
Authors
  Inanami O.  Asanuma T.  Inukai N.  Jin T.  Shimokawa S.  Kasai N.  Nakano M. 
  Sato F.  Kuwabara M.
Institution
  Faculty of Agriculture, Iwate University, Morioka, Japan.
Title
  The suppression of age-related accumulation of lipid peroxides in rat brain
  by administration of Rooibos tea (Aspalathus linearis).
Source
  Neuroscience Letters.  196(1-2):85-8, 1995 Aug 18.
Abstract
  The protective effects of Rooibos tea (RT), Aspalathus
  linearis, against damage to the central nervous system (CNS) accompanying
  aging were examined by both the thiobarbituric acid reaction (TBA) and
  magnetic resonance imaging (MRI) methods in brains of chronically RT-treated
  rats. Ad libitum administration of RT was begun with 3-month-old Wistar
  female rats and continued for 21 months. The contents of TBA reactive
  substances (TBARS) in the frontal cortex, occipital cortex, hippocampus and
  cerebellum in 24-month-old rats after administration with water were
  significantly higher than those in young rats (5 weeks old). However, no
  significant increase of TBARS was observed in RT-administered aged rats. When
  MR images of the brains of 24-month-old rats with and without RT as well as
  5-week-old rats were taken, a decrease of the signal intensity was observed
  in the cerebral cortex, hippocampus and cerebellum in MR images of aged rats
  without RT, whereas little change of the signal intensity was observed in MR
  images of the same regions of 24-month-old rats treated with RT, whose images
  were similar to those of young rats. These observations suggested that (1)
  the age-related accumulation of lipid peroxides in the brain was closely
  related to the morphological changes observed by MRI, and (2) chronic
  RT-administration prevented age-related accumulation of lipid peroxides in
  several regions of rat brain.
Re: possible biostasis with rooibos tea?
#362
Author: Randall Parker
Date: Thu, 27 Jan 2000 00:00
80 lines
4808 bytes
Doug,

Simple dumb question: Is rooibos tea something that is sold in stores? I 
never heard of it. 

I do like the CNS protection report though.

In <86ic5b$pu4$2@sylvester.vcn.bc.ca>, the exalted oberon@vcn.bc.ca Doug 
Skrecky opined:
> Subject: possible biostasis with rooibos tea?
> From: Doug Skrecky <oberon@vcn.bc.ca>
> Newsgroups: sci.life-extension, bionet.molbio.ageing
> 
> Citations: 1-2
> <1>
> Authors
>   Lamosova D.  Jurani M.  Greksak M.  Nakano M.  Vanekova M.
> Institution
>   Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences,
>   Ivanka pri Dunaji, Slovakia. LAMOSOVA@UBGZ.SAVBA.SK
> Title
>   Effect of Rooibos tea (Aspalathus linearis) on chick
>   skeletal muscle cell growth in culture.
> Source
>   Comparative Biochemistry & Physiology. Part C Pharmacology, Toxicology,
>   Endocrinology.  116(1):39-45, 1997 Jan.
> Abstract
>   Rooibos tea (RT) extract contains natural antioxidants and
>   scavenging agents. We investigated the effects of different concentrations of
>   RT extract in medium on growth and changes of growth parameters of cultured
>   chick embryonic skeletal muscle cells. Presence of 2, 10 and 100% of RT
>   extract in the culture of primary cells significantly inhibited cell
>   proliferation. The inhibition of cell growth reflected on decreased DNA, RNA
>   and protein contents in primary cell culture and fibroblasts and myoblasts.
>   The ability of the primary cells, fibroblasts and myoblasts to synthesize DNA
>   and protein in the presence of RT extract, measured as an amount of
>   [3H]thymidine and [3H]leucine incorporated into DNA and de novo synthesized
>   protein, corresponded with decreasing DNA and protein contents in all three
>   cell types. The inhibition effect of RT rose with increasing concentration of
>   the tea extract in the culture medium. Ornithine decarboxylase activity was
>   significantly affected only by 100% RT extract in every examined cell types.
>   These results suggest that the inhibitory effect of RT extract on the growth
>   of primary cells, fibroblasts and myoblasts is due to the potent scavenging
>   activity of the RT extract.
> 
> <2>
> Authors
>   Inanami O.  Asanuma T.  Inukai N.  Jin T.  Shimokawa S.  Kasai N.  Nakano M. 
>   Sato F.  Kuwabara M.
> Institution
>   Faculty of Agriculture, Iwate University, Morioka, Japan.
> Title
>   The suppression of age-related accumulation of lipid peroxides in rat brain
>   by administration of Rooibos tea (Aspalathus linearis).
> Source
>   Neuroscience Letters.  196(1-2):85-8, 1995 Aug 18.
> Abstract
>   The protective effects of Rooibos tea (RT), Aspalathus
>   linearis, against damage to the central nervous system (CNS) accompanying
>   aging were examined by both the thiobarbituric acid reaction (TBA) and
>   magnetic resonance imaging (MRI) methods in brains of chronically RT-treated
>   rats. Ad libitum administration of RT was begun with 3-month-old Wistar
>   female rats and continued for 21 months. The contents of TBA reactive
>   substances (TBARS) in the frontal cortex, occipital cortex, hippocampus and
>   cerebellum in 24-month-old rats after administration with water were
>   significantly higher than those in young rats (5 weeks old). However, no
>   significant increase of TBARS was observed in RT-administered aged rats. When
>   MR images of the brains of 24-month-old rats with and without RT as well as
>   5-week-old rats were taken, a decrease of the signal intensity was observed
>   in the cerebral cortex, hippocampus and cerebellum in MR images of aged rats
>   without RT, whereas little change of the signal intensity was observed in MR
>   images of the same regions of 24-month-old rats treated with RT, whose images
>   were similar to those of young rats. These observations suggested that (1)
>   the age-related accumulation of lipid peroxides in the brain was closely
>   related to the morphological changes observed by MRI, and (2) chronic
>   RT-administration prevented age-related accumulation of lipid peroxides in
>   several regions of rat brain.
> 
> 
> 
Re: possible biostasis with rooibos tea?
#352
Author: rjk3
Date: Fri, 28 Jan 2000 00:00
141 lines
5678 bytes
In article <MPG.12fa292d9a0d631298973c@news.onlynews.com>,
  Randall Parker <rgparker@west.net> wrote:
> Doug,
>
> Simple dumb question: Is rooibos tea something that is sold in
stores? I
> never heard of it.
>
> I do like the CNS protection report though.
>

And I wonder who sponsored the study.  A search on google turned up 603
web sites.  Here's one with a little history:

http://www.wimall.com/friend/indexwf.html

The plant is native to South Africa.

You can order it on line at:

http://www.savannahimports.com/tea.htm

It probably is beneficial, but I doubt if it's anything very dramatic.


> In <86ic5b$pu4$2@sylvester.vcn.bc.ca>, the exalted oberon@vcn.bc.ca
Doug
> Skrecky opined:
> > Subject: possible biostasis with rooibos tea?
> > From: Doug Skrecky <oberon@vcn.bc.ca>
> > Newsgroups: sci.life-extension, bionet.molbio.ageing
> >
> > Citations: 1-2
> > <1>
> > Authors
> >   Lamosova D.  Jurani M.  Greksak M.  Nakano M.  Vanekova M.
> > Institution
> >   Institute of Animal Biochemistry and Genetics, Slovak Academy of
Sciences,
> >   Ivanka pri Dunaji, Slovakia. LAMOSOVA@UBGZ.SAVBA.SK
> > Title
> >   Effect of Rooibos tea (Aspalathus linearis) on chick
> >   skeletal muscle cell growth in culture.
> > Source
> >   Comparative Biochemistry & Physiology. Part C Pharmacology,
Toxicology,
> >   Endocrinology.  116(1):39-45, 1997 Jan.
> > Abstract
> >   Rooibos tea (RT) extract contains natural antioxidants and
> >   scavenging agents. We investigated the effects of different
concentrations of
> >   RT extract in medium on growth and changes of growth parameters
of cultured
> >   chick embryonic skeletal muscle cells. Presence of 2, 10 and 100%
of RT
> >   extract in the culture of primary cells significantly inhibited
cell
> >   proliferation. The inhibition of cell growth reflected on
decreased DNA, RNA
> >   and protein contents in primary cell culture and fibroblasts and
myoblasts.
> >   The ability of the primary cells, fibroblasts and myoblasts to
synthesize DNA
> >   and protein in the presence of RT extract, measured as an amount
of
> >   [3H]thymidine and [3H]leucine incorporated into DNA and de novo
synthesized
> >   protein, corresponded with decreasing DNA and protein contents in
all three
> >   cell types. The inhibition effect of RT rose with increasing
concentration of
> >   the tea extract in the culture medium. Ornithine decarboxylase
activity was
> >   significantly affected only by 100% RT extract in every examined
cell types.
> >   These results suggest that the inhibitory effect of RT extract on
the growth
> >   of primary cells, fibroblasts and myoblasts is due to the potent
scavenging
> >   activity of the RT extract.
> >
> > <2>
> > Authors
> >   Inanami O.  Asanuma T.  Inukai N.  Jin T.  Shimokawa S.  Kasai
N.  Nakano M.
> >   Sato F.  Kuwabara M.
> > Institution
> >   Faculty of Agriculture, Iwate University, Morioka, Japan.
> > Title
> >   The suppression of age-related accumulation of lipid peroxides in
rat brain
> >   by administration of Rooibos tea (Aspalathus linearis).
> > Source
> >   Neuroscience Letters.  196(1-2):85-8, 1995 Aug 18.
> > Abstract
> >   The protective effects of Rooibos tea (RT), Aspalathus
> >   linearis, against damage to the central nervous system (CNS)
accompanying
> >   aging were examined by both the thiobarbituric acid reaction
(TBA) and
> >   magnetic resonance imaging (MRI) methods in brains of chronically
RT-treated
> >   rats. Ad libitum administration of RT was begun with 3-month-old
Wistar
> >   female rats and continued for 21 months. The contents of TBA
reactive
> >   substances (TBARS) in the frontal cortex, occipital cortex,
hippocampus and
> >   cerebellum in 24-month-old rats after administration with water
were
> >   significantly higher than those in young rats (5 weeks old).
However, no
> >   significant increase of TBARS was observed in RT-administered
aged rats. When
> >   MR images of the brains of 24-month-old rats with and without RT
as well as
> >   5-week-old rats were taken, a decrease of the signal intensity
was observed
> >   in the cerebral cortex, hippocampus and cerebellum in MR images
of aged rats
> >   without RT, whereas little change of the signal intensity was
observed in MR
> >   images of the same regions of 24-month-old rats treated with RT,
whose images
> >   were similar to those of young rats. These observations suggested
that (1)
> >   the age-related accumulation of lipid peroxides in the brain was
closely
> >   related to the morphological changes observed by MRI, and (2)
chronic
> >   RT-administration prevented age-related accumulation of lipid
peroxides in
> >   several regions of rat brain.
> >
> >
> >
>


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