🚀 go-pugleaf

sometimes what appears to be 'apathy' is 'just' a rational outcome of having
done all that one can do in the face of 'difficulty'.

and =always=, the thing to do with what's been referred to as 'depression'
is to acquire understanding... =never= to 'short-circuit' the nervous system
by attempting to chemically 're-engineer' it from outside.

there are other requirements which are outlined in AoK, Ap8.

Please Forgive me, Claude.

K. P. Collins (ken)

Claude de Contrecoeur wrote in message
<3796e8af.16349144@nn-tk004.ocn.ad.jp>...
>
>Int Clin Psychopharmacol 1997 Jul;12 Suppl 3:S29-33
>
>Early onset of action of amineptine.
>
>Freeman H
>
>Green College, Oxford, UK.
>
>A priority in the treatment of depression is to obtain rapid
>improvement at
>an early stage. Since depressed patients, who are often convinced that
>nothing can be done for them, may well have difficulty in adhering to
>the
>therapeutic management plan, they can be both uncooperative and
>neglectful
>of treatment measures. The rapid correction of this often resigned
>apathy
>is an ESSENTIAL aspect of treatment. According to a variety of
>clinical
>criteria, amineptine often achieves RAPID improvement, particularly on
>measures of psychomotor retardation. Initially, antidepressant
>medication
>is an essential measure in the relief of depressive symptoms, although
>subsequently, it may also become a complement to psychotherapeutic
>support.
>Amineptine has been shown to act directly on the dopaminergic pathway,
>unlike other antidepressants, which act on this system only via their
>effects on the serotonergic or noradrenergic systems.