Article View: sci.med.pharmacy
Article #149Re: Parkinson's medication problem
From: Steve Emerson
Date: Fri, 04 Apr 1997 00:00
Date: Fri, 04 Apr 1997 00:00
62 lines
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3694 bytes
In misc.health.alternative Matthew A. Emme <emme0002@gold.tc.umn.edu> wrote:
: In article <5hmn3f$qbn$1@nadine.teleport.com> Steve Emerson,
: semerson@teleport.com writes:
: >You can try NADH. It's new and a completely natural supplement, and
: >a study has found that it relieves Parkinson's symptoms.
: >It's now being used to treat Parkinson's.
: Most of the recent studies have not been able to verify this. You might
: want to take a look at "Treatment of Parkinson's disease with NADH.", by
: Dizdar N; K�agedal B; Lindvall B in the Acta Neurol Scand, 1994 Nov,
: 90:5, 345-7.
: Can you give me the name of the study that you saw that showed therapy
: with this med works, so I can take a look at it.
Title
Nicotinamide adenine dinucleotide (NADH)--a new therapeutic
approach to Parkinson's disease. Comparison of oral and
parenteral application.
Author
Birkmayer JG; Vrecko C; Volc D; Birkmayer W
Address
Birkmayer-Institut f�r Parkinsontherapie Vienna, Austria.
Source
Acta Neurol Scand Suppl, 146:1993, 32-5
Abstract
The reduced coenzyme nicotinamide adenine dinucleotide (NADH)
has been used as medication in 885 parkinsonian patients in an
open label trial. About half of the patients received NADH by
intravenous infusion, the other part orally by capsules. In
about 80% of the patients a beneficial clinical effect was
observed: 19.3% of the patients showed a very good (30-50%)
improvement of disability, 58.8% a moderate (10-30%)
improvement. 21.8% did not respond to NADH. Statistical
analysis of the improvement in correlation with the disability
prior to treatment, the duration of the disease and the age of
the patients revealed the following results: All these 3
parameters have a significant although weak influence on the
improvement. The disability before the treatment has a positive
regression coefficient (t value < 0.01). The duration of the
disease has a negative regression coefficient (< 0.01) and so
has the age a negative regression coefficient (t value < 0.05).
In other words younger patients and patients with a shorter
duration of disease have a better chance to gain a marked
improvement than older patients and patients with longer
duration of the disease. The orally applied form of NADH
yielded an overall improvement in the disability which was
comparable to that of the parenterally applied form.
--
Steve Emerson semerson@teleport.com
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X-Google-Language: ENGLISH,ASCII X-Google-Thread: 10583f,b24ccc7055543429 X-Google-Attributes: gid10583f,public X-Google-Thread: 1162c2,b24ccc7055543429 X-Google-Attributes: gid1162c2,public X-Google-Thread: 1045ed,b24ccc7055543429 X-Google-Attributes: gid1045ed,public X-Google-Thread: 105b48,b24ccc7055543429 X-Google-Attributes: gid105b48,public X-Google-Thread: f4552,b24ccc7055543429 X-Google-Attributes: gidf4552,public From: Steve Emerson <semerson@teleport.com> Subject: Re: Parkinson's medication problem Date: 1997/04/04 Message-ID: <5i2e2e$823$1@nadine.teleport.com> X-Deja-AN: 230614560 Distribution: world References: <333E27C6.4C2A@worldnet.att.net> <5hn306$gjl@epx.cis.umn.edu> Organization: Teleport - Portland's Public Access (503) 220-1016 Newsgroups: sci.med.pharmacy,sci.med,misc.health.alternative,sci.med.nursing,bionet.neuroscience