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Article #166Re: 1-benzyl-piperazine toxicology?
From: Bob Briggs
Date: Mon, 07 Sep 1998 00:00
Date: Mon, 07 Sep 1998 00:00
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Rhodium wrote in message <6t03g3$fbj$1@sparky.wolfe.net>... >Hi! > >I'd like to know any pharmacological and/or toxicological information anyone might have on >1-benzyl-piperazine, CAS [2759-28-6] for the freebase and [72878-35-4] for the hydrochloride. >I've already searched Altavista, Medline and Beilstein Abstracts to little avail. > >Any help is much appreciated! > > > > A CAS # search at http://chemfinder.camsoft.com takes you to Acros Organics (Fisher Chem website) which provides an MSDS (Material Safety Data Sheet) for 1-Benzylpiperazine. It is a corrosive and hazardous substance which may cause severe irritation and burns on skin and eye contact and when inhaled can cause chemical burns to the respiratory tract. For reasons not apparent to me, there are no studies reported on chronic exposure effects, mutagenicity, LD50, teratogenicity, carcinogenesis, reproductive effects or neurotoxicity. It has no RTECS #, which indicates that it is not scheduled for study. Sounds like a wide open area for toxicology research to me. Bob Briggs
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X-Google-Language: ENGLISH,ASCII-7-bit X-Google-Thread: f4886,8eacb6566e1b3093,start X-Google-Attributes: gidf4886,public X-Google-Thread: 103efd,8eacb6566e1b3093,start X-Google-Attributes: gid103efd,public X-Google-Thread: f4552,8eacb6566e1b3093,start X-Google-Attributes: gidf4552,public From: "Bob Briggs" <bobriggs@worldnet.att.net> Subject: Re: 1-benzyl-piperazine toxicology? Date: 1998/09/07 Message-ID: <6t15o2$i93@bgtnsc02.worldnet.att.net> X-Deja-AN: 388758098 References: <6t03g3$fbj$1@sparky.wolfe.net> X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 Organization: AT&T WorldNet Services Newsgroups: sci.med.pharmacy,sci.chem,bionet.toxicology