Re: MAOI Long Term Usage

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Article #172

#172

From: shapere
Date: Sat, 24 Oct 1998 00:00

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In article <705bpt$aeh$1@nnrp1.dejanews.com>,  <lsmith16@hotmail.com> wrote:
...
>Patients have reported to me that the mood enhancing
>and other positive effects recede after a month or
>two of use. Anyone have any knowledgeable input?

"Loss of antidepressant effect with long-term monoamine oxidase inhibitor
treatment without loss of monoamine oxidase inhibition" (J.J. Mann,
J. Clin. Psychopharm v.3 n.6 (12/83)) is one article on the subject.  I'm
sure there are others.

Anecdotally, MAOI tolerance does happen.  Some psychopharmacologists have
looked into ways to prevent antidepressant tolerance, although I'm not sure if
this has been studied methodically and/or with MAOIs specifically.

-elizabeth

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From: shapere@nospam.mit.edu
Subject: Re: MAOI Long Term Usage
Date: 1998/10/24
Message-ID: <70ru9e$8k@senator-bedfellow.MIT.EDU>
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