Article View: sci.nanotech
Article #855Re: Organic Machines?
From: Nick Szabo
Date: Fri, 22 Jan 1993 04:07
Date: Fri, 22 Jan 1993 04:07
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nsmca@acad3.alaska.edu writes: >Does nantech machines have to be mechanical? or can they be >genetic?? Ultimately nanomachines will be mechanical, since we can then use a much wider range of molecules than biology currently uses. For now, the path to full Drexler nanotech is following two major threads. The first of these is scaling of lithography down to the "deep sub-micron" scale, for the manufacture of quantum dots, designer catalysts, and minitiarized circuitry. Within a decade, we may see AFM arrays or other techniques used to mass-produce chips a 10 nm scale. The second is biotechnology, with liposomes (drug-carrying artificial membranes), monoclonal antibodies (cells programmed to be triggered by specific molecules), polymerase chain reaction (self-replication of DNA outside the cell, greatly accelerated over what nature can do), and gene-splicing as the basis for two new fields, protein engineering and metabolic engineering. We can already see these two fields starting to merge. Lithography is being used to program arrays of chemical reactions, for use in DNA sequencing, designer polymers, etc. Enzymes (protein catalysts) have been built into clay structures; these molecular cyborgs now help make such ubiquitious products as the corn syrup in your Pepsi. Soon we will see enzymes designed on a computer, programmed into DNA by wet-array-lithography, mass produced by gene-spliced bacteria, and then hooked onto lithographed structures to form catalysts orders of magnitude more proficient than today's. On the horizon are molecularly precise resists, or "nanoresists", for nanoscale lithography. Within two to three decades, lithography combined with a bit of post-processing will likely be able to produce molecularly precise parts, at which time we can start building mechanical machines and proto-assemblers along the lines Drexler envisions. In the meantime, biotech and lithography may bring many of the benefits ultimately envisioned for nanotechnology. -- Nick Szabo szabo@techboook.com
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arc1-ca.pugleaf.net!sparky!uunet!cs.utexas.edu!qt.cs.utexas.edu!yale.edu!newsserver.jvnc.net!rutgers!igor.rutgers.edu!planchet.rutgers.edu!nanotechShow Full Headers
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Path: arc1-ca.pugleaf.net!sparky!uunet!cs.utexas.edu!qt.cs.utexas.edu!yale.edu!newsserver.jvnc.net!rutgers!igor.rutgers.edu!planchet.rutgers.edu!nanotech From: szabo@techbook.com (Nick Szabo) Newsgroups: sci.nanotech Subject: Re: Organic Machines? Message-ID: <Jan.21.23.07.19.1993.5333@planchet.rutgers.edu> Date: 22 Jan 93 04:07:20 GMT Sender: nanotech@planchet.rutgers.edu Organization: TECHbooks --- Public Access UNIX --- (503) 220-0636 Lines: 43 Approved: nanotech@aramis.rutgers.edu