Article View: sci.physics
Article #8645Ab/Ag energetics
From: Ed Stokes
Date: Fri, 27 Mar 1992 12:51
Date: Fri, 27 Mar 1992 12:51
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1388 bytes
I am interested in the physics of antibody-antigen complexes.
None of the biochemistry and immunology books I've consulted
has any real parametric data, and I'd appreciate a pointer.
Four questions come to mind:
1 - What is the range of binding energy that holds an antibody
antigen complex together ?
2 - What is the relationship between this binding energy and
the reaction rate constant K, i.e.:
K
Ab + Ag ---> AbAg
<---
2 - Is the primary interaction between antibody and antigen
of a dipole-dipole nature ?
3 - What is the physical size of a typical IgG antibody ?
Thanks in advance.
Ed Stokes
ebstokes@crd.ge.com
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X-Google-Language: ENGLISH,ASCII-7-bit X-Google-Thread: 107c0a,30b0b9a9113b0c01,start X-Google-Attributes: gid107c0a,public X-Google-Thread: 1119a6,30b0b9a9113b0c01,start X-Google-Attributes: gid1119a6,public X-Google-Thread: 10b271,30b0b9a9113b0c01,start X-Google-Attributes: gid10b271,public X-Google-ArrivalTime: 1992-03-27 04:51:54 PST Path: arc1-ca.pugleaf.net!sparky!uunet!crdgw1!maxwell!ebstokes From: ebstokes@maxwell.crd.ge.com (Ed Stokes) Newsgroups: sci.physics,sci.bio,bionet.general Subject: Ab/Ag energetics Message-ID: <29072@crdgw1.crd.ge.com> Date: 27 Mar 92 12:51:54 GMT Sender: news@crdgw1.crd.ge.com Followup-To: sci.physics Organization: GE Corp. Research & Development, Schenectady, NY Lines: 25