🚀 go-pugleaf

Postdoctoral position as posted on PostdocJobs.com:

http://www.PostdocJobs.com
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We seek an individual interested in the 
mechanistic exploration of a novel lacrimal-
specific human mitogen, �lacritin' (Sanghi et 
al, J. Mol. Biol. 310:127�139, 2001; cover 
article). The recently cDNA cloned factor is 
both an autocrine enhancer of lacrimal 
secretion, and a downstream mitogen via an 
EGF-like signaling pathway(s) involving 
calcium and tyrosine phosphorylation but 
lacking involvement of Erk1/Erk2. Both lacritin 
expression and cell types responsive to 
lacritin are very restricted.

A background in mitogenic signaling or 
exocrine secretion would be very helpful. Also 
useful would be a working knowledge of G-
protein-coupled receptors. The project will 
focus on elucidation of downstream signaling 
events and the secretory pathway(s) affected. 
The Laurie lab seeks to give students and 
postdocs the opportunity to develop into 
independent scientists by providing the 
freedom to explore state-of-the-art science in 
a highly collaborative institutional environment 
that is well-funded. 

Description of Institution 
In its 15th annual "America's Best Colleges" 
issue (September 2001), U.S. News & World 
Report ranked the University of Virginia the 
nation's #2 public university and 21st among 
all US national universities. Only two other 
public universities are in the top 25: the 
University of California-Berkeley at 20th and 
the University of Michigan, 25th. This position 
is located in the Health Science Center's 
Department of Cell Biology (hsc.virginia.edu/
medicine/basic-sci/cellbio/), ranked #4 
nationally by NIH for research funding. 



For more information, please visit the Postdoc Jobs website:

http://www.PostdocJobs.com