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Article #196PostdocJobs.com => Postdoctoral Researcher - Transcription factor genomics
From: PostdocJobs.com
Date: Thu, 04 Oct 2001 03:23
Date: Thu, 04 Oct 2001 03:23
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4131 bytes
Postdoctoral position as posted on Postdoc Jobs website: http://www.PostdocJobs.com ------------------------------ The DOE Joint Genome Institute and Lawrence Livermore National Laboratory jointly have an immediate opening for a postdoctoral researcher to conduct research in the field of transcription factor genomics. This research will investigate the Kr๏ฟฝppel-type, C2H2 gene family of putative transcription factors in vertebrates. Six to seven hundred of these genes exist in the human genome and comprise > 1/3 of all human transcription factors. The research will focus on the ~265 such genes found on human chromosome 19 which have recently been characterized in some detail in both mouse and man (see Dehal et. al. 2001, Science). The chromosome19 genes are organized largely in paralog clusters and are evolving rapidly in both primate and murine lineages. A central goal of the research is to identify binding sites in the genome for these putative transcription factors, and thereby their likely regulatory targets. Longer term it is hoped that the transcription complexes involving these factors can be characterized and that their functional evolution in vertebrates can be understood in some measure based on evolutionary comparative studies. Will work under general supervision, reporting to project investigator and interacting with other members of a newly forming, multi-lab working group in regulatory genomics. Conduct transcription factor genomics research using a wide range of techniques in molecular biology and biochemistry. Develop new laboratory protocols and methods. Present overviews of progress in the experimental work at regular meetings of the JGI regulatory genomics group. Independently develop research projects through peer review and evaluation. Present results of research at national and international conferences. Publish completed research in peer-reviewed literature. Create and maintain strong relationship to and knowledge of closely related research coupled to the JGI programs in comparative and regulatory genomics. Requires recent Ph.D. (within last five years) in molecular biology, biochemistry, cell biology or related discipline. Experience in molecular biology research. Knowledge of literature in some aspect of transcription factor biology. Ability to develop independent research projects as demonstrated through publication of peer-reviewed manuscripts. Effective communication skills as demonstrated through presentation of seminars, oral presentations at meetings and/or teaching lectures. Demonstrated ability with computers for manuscript preparation and data analysis. Excellent interpersonal skills with a commitment to and demonstrated ability to perform collaborative research in a team environment. Documented publication record. Salary is open, and the position is available for two years in Walnut Creek, CA. The selected candidate will receive a full competitive benefits package. For more information, please visit Postdoc Jobs website: http://www.PostdocJobs.com
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