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Article #196

PostdocJobs.com => Postdoctoral Researcher - Transcription factor genomics

#196
From: PostdocJobs.com
Date: Thu, 04 Oct 2001 03:23
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Postdoctoral position as posted on Postdoc Jobs website:

http://www.PostdocJobs.com

------------------------------

The DOE Joint Genome Institute and Lawrence Livermore National
Laboratory jointly have an immediate opening for a postdoctoral
researcher to conduct research in the field of transcription factor
genomics. This research will investigate the Kr๏ฟฝppel-type, C2H2 gene
family of putative transcription factors in vertebrates. Six to seven
hundred of these genes exist in the human genome and comprise > 1/3 of
all human transcription factors. The research will focus on the ~265
such genes found on human chromosome 19 which have recently been
characterized in some detail in both mouse and man (see Dehal et. al.
2001, Science). The chromosome19 genes are organized largely in
paralog clusters and are evolving rapidly in both primate and murine
lineages. A central goal of the research is to identify binding sites
in the genome for these putative transcription factors, and thereby
their likely regulatory targets. Longer term it is hoped that the
transcription complexes involving these factors can be characterized
and that their functional evolution in vertebrates can be understood
in some measure based on evolutionary comparative studies. Will work
under general supervision, reporting to project investigator and
interacting with other members of a newly forming, multi-lab working
group in regulatory genomics.

Conduct transcription factor genomics research using a wide range of
techniques in molecular biology and biochemistry. Develop new
laboratory protocols and methods. Present overviews of progress in the
experimental work at regular meetings of the JGI regulatory genomics
group.
Independently develop research projects through peer review and
evaluation. Present results of research at national and international
conferences. Publish completed research in peer-reviewed literature.
Create and maintain strong relationship to and knowledge of closely
related research coupled to the JGI programs in comparative and
regulatory genomics.

Requires recent Ph.D. (within last five years) in molecular biology,
biochemistry, cell biology or related discipline. Experience in
molecular biology research. Knowledge of literature in some aspect of
transcription factor biology. Ability to develop independent research
projects as demonstrated through publication of peer-reviewed
manuscripts. Effective communication skills as demonstrated through
presentation of seminars, oral presentations at meetings and/or
teaching lectures. Demonstrated ability with computers for manuscript
preparation and data analysis. Excellent interpersonal skills with a
commitment to and demonstrated ability to perform collaborative
research in a team environment. Documented publication record.

Salary is open, and the position is available for two years in Walnut
Creek, CA. The selected candidate will receive a full competitive
benefits package.

For more information, please visit Postdoc Jobs website:

http://www.PostdocJobs.com
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Subject: PostdocJobs.com => Postdoctoral Researcher - Transcription factor genomics
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