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Article #201PostdocJobs.com => Post-doc in parasite adhesion
From: PostdocJobs.com
Date: Mon, 08 Oct 2001 01:06
Date: Mon, 08 Oct 2001 01:06
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2585 bytes
--------------------------- Postdoctoral position as posted on the Postdoc Jobs website: http://www.PostdocJobs.com --------------------------- An NIH-supported postdoctoral position is available immediately to define the function of parasite adhesive proteins in host cell invasion by Toxoplasma gondii. T. gondii is an opportunistic protozoan parasite that can cause severe disease (encephalitis, retinitis, birth-defects) in humans and animals. The parasite is highly tractable, easily cultured in vitro, has excellent animal models and is amenable to genetic manipulation and thus is an excellent model system to study the molecular and cell biology of a eukaryotic pathogen. T. gondii actively invades target cells using adhesive proteins stored in secretory granules. These proteins contain phylogenetically conserved adhesive domains thought to recognize receptors expressed on a wide variety of target cells. The project will include creating transgenic Toxoplasma expressing adhesive protein mutants and examining the resulting invasion phenotypes. Candidates must have a Ph.D. and/or M.D. or equivalent degree and a strong background in biochemistry and molecular biology. Experience in parasitology is not necessary, but would be an asset. Applicants should provide (preferably as attachments via e-mail) a cover letter, curriculum vitae, and the names of three individuals familiar with the applicant's credentials. For more information, please visit Postdoc Jobs website http://www.PostdocJobs.com ----------------------------
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