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Article #616Re: Gene Pool
From: Aimee Yermish
Date: Wed, 08 Feb 1989 21:53
Date: Wed, 08 Feb 1989 21:53
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In article <10276@ut-emx.UUCP> ethan@ut-emx.UUCP (Ethan Tecumseh Vishniac) writes: >Not being a geneticist, I have frequently wondered, but never looked into, >the question of why an infrequent mutation like Tay-Sachs, which has such >a devastating effect on those unfortunates who are homozygous for it, has >such a relatively *high* incidence among Ashkenzaic Jewry (I believe that >1/30 individuals is heterozygous). I think that a large part of the answer is that Ashkenazi Jews are a (compared to the whole world) small population with relatively strong (although not so much in recent times) beliefs against intermarriage. As far as what the defect is or how it could possibly interact with other diseases, I don't know what is known, but might be able to look it up if you are interested. --Aimee -- Aimee Yermish ayermish@asylum.sf.ca.us Program in Cancer Biology ayermish@portia.stanford.edu Stanford University 415-594-9268
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Path: arc1-ca.pugleaf.net!utzoo!utgpu!jarvis.csri.toronto.edu!mailrus!ames!oli-stl!asylum!ayermish From: ayermish@asylum.SF.CA.US (Aimee Yermish) Newsgroups: sci.research,talk.politics.misc,sci.bio Subject: Re: Gene Pool Message-ID: <1095@asylum.SF.CA.US> Date: 8 Feb 89 21:53:46 GMT References: <674@intvax.UUCP> <1252@meccsd.MECC.MN.ORG> <1254@meccsd.MECC.MN.ORG> <5579@ncsugn.ncsu.edu> <10276@ut-emx.UUCP> Reply-To: ayermish@asylum.UUCP (Aimee Yermish) Followup-To: sci.research Distribution: na Organization: The Asylum; Belmont, CA Lines: 20