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1 total messages Started by PostdocJobs.com Sun, 13 Apr 2003 00:46
PostdocJobs.com -> position in biophysics
#725
Author: PostdocJobs.com
Date: Sun, 13 Apr 2003 00:46
40 lines
3240 bytes
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Postdoctoral position as posted on Postdoc Jobs website:

http://www.PostdocJobs.com
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Cochlear outer hair cells convert sound-induced mechanical vibration
into electrical signal at their stereocilia. They also perform reverse
transduction, in which their cell body acts as an actuator. Such a
combinations of cellular properties can be the basis for a feedback
loop in the inner ear that brings about the ear's sensitivity as well
as frequency selectivity. We investigate the cellular and molecular
mechanisms of these cells in connection with their biological roles
with membrane biophysical means. Two main current projects are:

[1] Clarify the motile mechanism of outer hair cells. We are examining
prestin, the novel membrane protein that is the motor's constituent,
and the motor in outer hair cells to clarify the possible involvement
of other elements in the hair cell motors. We further plan to study
structure and function relationship of prestin.

[2] Study potassium channels in outer hair cells. We found that basal
turn hair cells have usually fast-activating potassium channels, which
we hypothesize hold a key to clarifying the biological role. We
investigate detailed properties of these channels.

The applicant must be within five (5) years of doctorate. Please have
three (3) reference letters forwarded. Experience in patch-clamping
and other electrophysiological methods is desirable. A background in
physics or theoretical analysis is appreciated.

For more information, please visit
http://www.postdocjobs.com/jobs/302934.shtml

For international professionals who need work visas or green card to
work in the United States, please visit the following page for more
info:

http://www.postdocjobs.com/visa/
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