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Started by PostdocJobs.com
Sun, 13 Apr 2003 00:46
PostdocJobs.com -> position in biophysics
Author: PostdocJobs.com
Date: Sun, 13 Apr 2003 00:46
Date: Sun, 13 Apr 2003 00:46
40 lines
3240 bytes
3240 bytes
------------------- Postdoctoral position as posted on Postdoc Jobs website: http://www.PostdocJobs.com ------------------- Cochlear outer hair cells convert sound-induced mechanical vibration into electrical signal at their stereocilia. They also perform reverse transduction, in which their cell body acts as an actuator. Such a combinations of cellular properties can be the basis for a feedback loop in the inner ear that brings about the ear's sensitivity as well as frequency selectivity. We investigate the cellular and molecular mechanisms of these cells in connection with their biological roles with membrane biophysical means. Two main current projects are: [1] Clarify the motile mechanism of outer hair cells. We are examining prestin, the novel membrane protein that is the motor's constituent, and the motor in outer hair cells to clarify the possible involvement of other elements in the hair cell motors. We further plan to study structure and function relationship of prestin. [2] Study potassium channels in outer hair cells. We found that basal turn hair cells have usually fast-activating potassium channels, which we hypothesize hold a key to clarifying the biological role. We investigate detailed properties of these channels. The applicant must be within five (5) years of doctorate. Please have three (3) reference letters forwarded. Experience in patch-clamping and other electrophysiological methods is desirable. A background in physics or theoretical analysis is appreciated. For more information, please visit http://www.postdocjobs.com/jobs/302934.shtml For international professionals who need work visas or green card to work in the United States, please visit the following page for more info: http://www.postdocjobs.com/visa/ --------------------------------
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