🚀 go-pugleaf

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Post-doctoral position as posted on Postdoc Jobs website:

http://www.PostdocJobs.com
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Postdoctoral opportunity in University of California, Davis 

A postdoctoral position is available for a recent Ph.D. to study
molecular mechanisms of autoimmunity and autoimmune pathogenesis. A
major project concerns the characterization of B and T cell
determinants of megalin/gp330 relevant to its role as the autoantigen
of Heymann nephritis. A principal approach involves generation of
recombinant antigenic proteins in baculovirus expression systems.
Studies are presently focused on the identification of major
conformational epitopes and the role of posttranslational
modifications in the induction of pathogenic autoimmunity. The
analysis will progress towards an understanding of both cellular and
antibody-mediated mechanisms of disease. Novel approaches involving
both structurally defined antigens and monoclonal antibodies have been
proposed to elucidate the pathway for propagation of the autoimmune
responses. Molecular studies of megalin are also interesting in regard
to its cellular function and its relationship to the LDL receptor
family of proteins. Applications are invited from self-motivated
individuals with a strong background in protein biochemistry,
molecular immunology and molecular biology. Experience in baculovirus
cloning and expression, Western blot and lectin blot analysis and/or
phage display technology is desirable. UC Davis provides a highly
collaborative research environment with excellent facilities. Salary
is commensurate with experience. Email responses are encouraged.

For more information, please visit the PostdocJobs website:

http://www.postdocjobs.com/jobs/302902.shtml
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