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Article #1417Re: HIV screening "window" & PCR
From: Falk Fish
Date: Mon, 29 May 1995 00:00
Date: Mon, 29 May 1995 00:00
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1217 bytes
The current window's median is about 6 months. Theoretically, PCR should reduce the window, however, the actual performance does not always live to its expectations. The problem may emanate from: 1. Specimen preparation problems; 2. The virus is not located in circulating periferal lymphocytes at the early stages of the infection. Therefore, even very efficient amplification methods are unable to detect. The are some groups working on other methods for window shrinking with some impressive results. You should realize also that the window is an estimate: it is difficult, if not impossible, to know when the active infection started. Falk Fish
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X-Google-Language: ENGLISH,ASCII-7-bit X-Google-Thread: 10eaff,16fac2654334c648 X-Google-Attributes: gid10eaff,public From: ila2027@ZEUS.DATASRV.CO.IL (Falk Fish) Subject: Re: HIV screening "window" & PCR Date: 1995/05/29 Message-ID: <Pine.3.89.1.2.9505300011.B18463-0100000@zeus.datasrv.co.il> X-Deja-AN: 103526480 distribution: world sender: daemon@net.bio.net references: <pkramer-2805950811160001@pkramer.connix.com> organization: BIOSCI International Newsgroups for Molecular Biology newsgroups: bionet.diagnostics