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Article #2116

Re: Does HIV kill cells?

#2116
From: Matthew P Wiener
Date: Thu, 24 Mar 1994 20:04
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In article <2msg2u$ste@s.ms.uky.edu>, mpm@seqanal (Mark Mattson) writes:
>With respect to HIV itself, I think it is clear that the virus can
>kill neurons in the CNS, apparently by stimulating an influx of
>calcium.  It is not clear (to me, anyway) whether this phenomenon
>involves killing of uninfected neurons by extracellular holovirus or
>whether it's only infected cells that die.

HIV does not, apparently, infect neurons.  It infects microglia, and
causes them to join together.
-- 
-Matthew P Wiener (weemba@sagi.wistar.upenn.edu)
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References: <1994Mar24.085208.16835@leeds.ac.uk> <2msg2u$ste@s.ms.uky.edu>

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From: weemba@sagi.wistar.upenn.edu (Matthew P Wiener)
Newsgroups: bionet.general,bionet.cellbiol,bionet.molbio.hiv,bionet.virology,bionet.immunology,sci.bio
Subject: Re: Does HIV kill cells?
Followup-To: sci.bio
Date: 24 Mar 1994 20:04:10 GMT
Organization: The Wistar Institute of Anatomy and Biology
Lines: 11
Message-ID: <2msrnq$gtb@netnews.upenn.edu>
References: <1994Mar24.085208.16835@leeds.ac.uk> <2msg2u$ste@s.ms.uky.edu>
Reply-To: weemba@sagi.wistar.upenn.edu (Matthew P Wiener)
NNTP-Posting-Host: sagi.wistar.upenn.edu
In-reply-to: mpm@seqanal.mi.uky.edu (Mark Mattson)