TLC of Thiols

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Article #2312

#2312

From: Dinah Thiers Farrington
Date: Wed, 07 Feb 1996 00:00

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searching for a TLC solvent system, and gotten unusual results. I am
using silica plates, and I<2 to develop them. Instead of dark spots, I
see a large white spot  with a rim of darker staining. Absolutely
nothing in the white spot is picking up the iodine, and I'm quite sure
this is not something contaminating the silica before the plate is
developed. Has anyone seen this behavior?  Any explanation  of this, or
anyreferences describing this would be greatly appreciated. This
happened so far with solvents of 1:99 ratio of methanol to CH<2Cl<2  and
5:95 CH<2Cl<2 to ether.( Whatis the explanation for I<2 marking the compounds,
anyway?)
      
     2. I'm trying to visualize Br-CH<2CH<2CH<2-SH and
SH-CH<2CH<2CH<2-OH BY this method. Anyone who has separated short chain 
thiols  could help me greatly by sending me a note about what systems
they found successful.
                                        Thank You,
                                        Dinah Farrington

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From: farrid@lib107.its.rpi.edu (Dinah Thiers Farrington)
Subject: TLC of Thiols
Date: 1996/02/07
Message-ID: <4faj00$igc@lib107.its.rpi.edu>
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          i am a graduate student with 2 questions: 1. I have been
organization: Rensselaer Polytechnic Institute, Troy, NY.
keywords: Dear Readers,
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