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Tetrodotoxin (4368-28-9), a toxin from the globe fish ovaries and liver (Merck Index 12th Ed.).  There
is a much longer IUPAC name of course, but I don't have time to type it.

--


Dr. Henry Boyter, Jr. Ph.D. Chemist

The opinions of Dr. Boyter are provided for informational
purposes only and should not be used as advice.  No
warranty or expression of professionalism is implied.

**********************************************************
Joe Smith wrote in message <35E19DDA.DB6970A5@erols.com>...
Can someone please tell me what TTX is? I was told that it is a
naturally occuring toxin, but I have been unable to find any info on
it.  A formula or full name would be most helpful.  Thanks.

melenkir@hotmail.com

Joe Smith <silence@erols.com> wrote in article
<35E19DDA.DB6970A5@erols.com>...
> Can someone please tell me what TTX is? I was told that it is a
> naturally occuring toxin, but I have been unable to find any info on
> it.  A formula or full name would be most helpful.  Thanks.
> 
> melenkir@hotmail.com
> 
> 
Tetrodotxin; C11 H17 N3 O8.HBr

...unashamedly filched from the site at;

http://fugu.hgmp.mrc.ac.uk/fugu/pffp/toxin.html

Doug Barr <barrdm@NOSPAM.bp.com> wrote in article
<01bdcf84$aec1a180$e57866a1@EUHULW524.hul.eu.bp.com>...
> 
 <snip>

yeah yeah...

Tetrodotoxin;  C11 H17 N3 O8 (HBr is for crystallisation only)

probably tetrodotoxin, which is the puffer fish or fugu toxin.

Mike Corbett

TTX, Tetrodotoxin, is a sodium channel blocker.  It binds to the receptors of
sodium channels preventing them to allow passage of sodium ions through a
membrane.

Why it is a toxin, is that it is poisonous and will kill a human at certain
levels.  The toxic mechanism of action is the blocking of sodium channels,
usually voltage gated, and the subsequent loss of an action potential which
would be required to release calcium in a muscle cell-for example.  Thus the
muscle is unable to contract or enters in a state of tetany.

The allure of the blowfish, when properly prepared, gives one the tingling
sensation upon tasting the meat.  Of course, this is at low levels; hopefully
if you want to walk away from your meal.

TTX poisoning is generally treated by artificial respiration and subsequent
connection of the patient to a ventilator.  TTX works very similar to STX, or
Saxitoxin which is from clams and mussels who feed during a red tide.

Not all sodium channel blockers are bad.  Most local anesthetics are sodium
channel blockers which will work on Type iii-iV pain receptors, blocking
their depolarization and allowing the doc or dentist to work without you
feeling every nick, prick, and cut.

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and its cheap too ! just 98.00$ per gram....

classified9588@my-dejanews.com wrote:

> TTX, Tetrodotoxin, is a sodium channel blocker.  It binds to the receptors of
> sodium channels preventing them to allow passage of sodium ions through a
> membrane.
>
> Why it is a toxin, is that it is poisonous and will kill a human at certain
> levels.  The toxic mechanism of action is the blocking of sodium channels,
> usually voltage gated, and the subsequent loss of an action potential which
> would be required to release calcium in a muscle cell-for example.  Thus the
> muscle is unable to contract or enters in a state of tetany.
>
> The allure of the blowfish, when properly prepared, gives one the tingling
> sensation upon tasting the meat.  Of course, this is at low levels; hopefully
> if you want to walk away from your meal.
>
> TTX poisoning is generally treated by artificial respiration and subsequent
> connection of the patient to a ventilator.  TTX works very similar to STX, or
> Saxitoxin which is from clams and mussels who feed during a red tide.
>
> Not all sodium channel blockers are bad.  Most local anesthetics are sodium
> channel blockers which will work on Type iii-iV pain receptors, blocking
> their depolarization and allowing the doc or dentist to work without you
> feeling every nick, prick, and cut.
>
> -----== Posted via Deja News, The Leader in Internet Discussion ==-----
> http://www.dejanews.com/rg_mkgrp.xp   Create Your Own Free Member Forum