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2 messages
2 total messages Started by Claude de Contrecoeur Thu, 22 Jul 1999 00:00
Rapid onset of action of Amineptine on depression
#130
Author: Claude de Contrecoeur
Date: Thu, 22 Jul 1999 00:00
29 lines
1815 bytes
Int Clin Psychopharmacol 1997 Jul;12 Suppl 3:S29-33 

Early onset of action of amineptine.

Freeman H

Green College, Oxford, UK. 

A priority in the treatment of depression is to obtain rapid
improvement at
an early stage. Since depressed patients, who are often convinced that
nothing can be done for them, may well have difficulty in adhering to
the
therapeutic management plan, they can be both uncooperative and
neglectful
of treatment measures. The rapid correction of this often resigned
apathy
is an ESSENTIAL aspect of treatment. According to a variety of
clinical
criteria, amineptine often achieves RAPID improvement, particularly on
measures of psychomotor retardation. Initially, antidepressant
medication
is an essential measure in the relief of depressive symptoms, although
subsequently, it may also become a complement to psychotherapeutic
support.
Amineptine has been shown to act directly on the dopaminergic pathway,
unlike other antidepressants, which act on this system only via their
effects on the serotonergic or noradrenergic systems. 
Re: Rapid onset of action of Amineptine on depression
#131
Author: Ken Collins
Date: Thu, 22 Jul 1999 00:00
44 lines
2421 bytes
sometimes what appears to be 'apathy' is 'just' a rational outcome of having
done all that one can do in the face of 'difficulty'.

and =always=, the thing to do with what's been referred to as 'depression'
is to acquire understanding... =never= to 'short-circuit' the nervous system
by attempting to chemically 're-engineer' it from outside.

there are other requirements which are outlined in AoK, Ap8.

Please Forgive me, Claude.

K. P. Collins (ken)

Claude de Contrecoeur wrote in message
<3796e8af.16349144@nn-tk004.ocn.ad.jp>...
>
>Int Clin Psychopharmacol 1997 Jul;12 Suppl 3:S29-33
>
>Early onset of action of amineptine.
>
>Freeman H
>
>Green College, Oxford, UK.
>
>A priority in the treatment of depression is to obtain rapid
>improvement at
>an early stage. Since depressed patients, who are often convinced that
>nothing can be done for them, may well have difficulty in adhering to
>the
>therapeutic management plan, they can be both uncooperative and
>neglectful
>of treatment measures. The rapid correction of this often resigned
>apathy
>is an ESSENTIAL aspect of treatment. According to a variety of
>clinical
>criteria, amineptine often achieves RAPID improvement, particularly on
>measures of psychomotor retardation. Initially, antidepressant
>medication
>is an essential measure in the relief of depressive symptoms, although
>subsequently, it may also become a complement to psychotherapeutic
>support.
>Amineptine has been shown to act directly on the dopaminergic pathway,
>unlike other antidepressants, which act on this system only via their
>effects on the serotonergic or noradrenergic systems.
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