🚀 go-pugleaf

Herbert Donaldson wrote:

> Does anybody have any ideas about what I can try?  Another medication to
> relieve Parkinson's symptoms?  Another way of taking the Sinemet?  A
> different dosage?  I would really appreciate any help with this, since I
> am feeling very discouraged.  Thank you.
> 
> Herbert Donaldson


I've heard some interesting information about the benefit of eating Fava
Beans (Broad Beans) for Parkinson's.  You might do a Medline search
about this.

Richard
-- 
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	Richard Grossman, Lic.Ac., O.M.D., Ph.D.
	Voice Mail - (310) 358-6125
	http://acudoc.com/acudoc

	Please remove the *** from my address if you wish to reply.  This
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***************************************************************************

You can try NADH.  It's new and a completely natural supplement, and
a study has found that it relieves Parkinson's symptoms.
It's now being used to treat Parkinson's.  Taking l-dopa (Sinemet)
with deprenyl is not recommended and has been found to decrease life
expectancy.

In misc.health.alternative Herbert Donaldson <HerbertDonaldson@worldnet.att.net> wrote:
: I have very early stage Parkinson's Disease.  It primarily impacts on my
: ability to walk up inclines or stairs and to get out of a chair.  I am
: taking Eldepryl with no problems.  Initially, I took Amantadine for the
: symptoms and it relieved my symptoms, but soon lost its effectiveness. I
: have now been taking Sinemet for several months.  First I was on a dose
: of 10/100 three times a day.  I could not tolerate that at all and felt
: constantly nauseous.  Then I went to 50/200, which I have tolerated
: better, but I still have problems with it.  (Also briefly tried 25/250,
: which was worse.)  I need to take Mylanta and Zantac several times a day
: in order to reduce feelings of nausea.  I now take Sinemet once a day
: after lunch.  I still have some nausea from it and taking it once a day
: is not sufficient for helping the Parkinson's symptoms, but I am
: reluctant to take it more often due to a chance of increased nausea. 
: Does anybody have any ideas about what I can try?  Another medication to
: relieve Parkinson's symptoms?  Another way of taking the Sinemet?  A
: different dosage?  I would really appreciate any help with this, since I
: am feeling very discouraged.  Thank you.

: Herbert Donaldson

-- 


Steve Emerson     semerson@teleport.com

In article <5hmn3f$qbn$1@nadine.teleport.com> Steve Emerson,
semerson@teleport.com writes:
>You can try NADH.  It's new and a completely natural supplement, and
>a study has found that it relieves Parkinson's symptoms.
>It's now being used to treat Parkinson's.  



Most of the recent studies have not been able to verify this.  You might
want to take a look at  "Treatment of Parkinson's disease with NADH.", by
Dizdar N; K�agedal B; Lindvall B in the Acta Neurol Scand, 1994 Nov,
90:5, 345-7.  

Can you give me the name of the study that you saw that showed therapy
with this med works, so I can take a look at it.


<cuts>


Matt

Richard Grossman, L.Ac., O.M.D., Ph.D. (***acudoc@acudoc.com) wrote:
: Herbert Donaldson wrote:

: > Does anybody have any ideas about what I can try?  Another medication to
: > relieve Parkinson's symptoms?  Another way of taking the Sinemet?  A
: > different dosage?  I would really appreciate any help with this, since I
: > am feeling very discouraged.  Thank you.
: > 
: > Herbert Donaldson


: I've heard some interesting information about the benefit of eating Fava
: Beans (Broad Beans) for Parkinson's.  You might do a Medline search
: about this.

: Richard
: -- 


	...Something else to try is "Mufuna pruiens" - Velvet bean.   my
1997 "allies" (formally ...of the jungle) catalog says:

"The seeds are a good source of L-Dopamine being used to treat
Parkingson's Disease in a very effective manner.   Currently the seeds
have become quite popularly known as having aphrodisiac qualities."
Seed Packet - $3.00

Allies - p.o.box 2422 Sabastopol, CA 95473 (catalog $2)
 
In addition to what they say about them, I have heard they have been used
in India for Parkingson's.


		...Rodney

In misc.health.alternative Matthew A. Emme <emme0002@gold.tc.umn.edu> wrote:
: In article <5hmn3f$qbn$1@nadine.teleport.com> Steve Emerson,
: semerson@teleport.com writes:
: >You can try NADH.  It's new and a completely natural supplement, and
: >a study has found that it relieves Parkinson's symptoms.
: >It's now being used to treat Parkinson's.  



: Most of the recent studies have not been able to verify this.  You might
: want to take a look at  "Treatment of Parkinson's disease with NADH.", by
: Dizdar N; K�agedal B; Lindvall B in the Acta Neurol Scand, 1994 Nov,
: 90:5, 345-7.  

: Can you give me the name of the study that you saw that showed therapy
: with this med works, so I can take a look at it.


   Title
          Nicotinamide adenine dinucleotide (NADH)--a new therapeutic
          approach to Parkinson's disease. Comparison of oral and
          parenteral application.
          
   Author
          Birkmayer JG; Vrecko C; Volc D; Birkmayer W
          
   Address
          Birkmayer-Institut f�r Parkinsontherapie Vienna, Austria.
          
   Source
          Acta Neurol Scand Suppl, 146:1993, 32-5
          
   Abstract
          The reduced coenzyme nicotinamide adenine dinucleotide (NADH)
          has been used as medication in 885 parkinsonian patients in an
          open label trial. About half of the patients received NADH by
          intravenous infusion, the other part orally by capsules. In
          about 80% of the patients a beneficial clinical effect was
          observed: 19.3% of the patients showed a very good (30-50%)
          improvement of disability, 58.8% a moderate (10-30%)
          improvement. 21.8% did not respond to NADH. Statistical
          analysis of the improvement in correlation with the disability
          prior to treatment, the duration of the disease and the age of
          the patients revealed the following results: All these 3
          parameters have a significant although weak influence on the
          improvement. The disability before the treatment has a positive
          regression coefficient (t value < 0.01). The duration of the
          disease has a negative regression coefficient (< 0.01) and so
          has the age a negative regression coefficient (t value < 0.05).
          In other words younger patients and patients with a shorter
          duration of disease have a better chance to gain a marked
          improvement than older patients and patients with longer
          duration of the disease. The orally applied form of NADH
          yielded an overall improvement in the disability which was
          comparable to that of the parenterally applied form.
          

-- 


Steve Emerson     semerson@teleport.com

Do you know of any placebo controlled trials of NADH as therapy for PD?
The study you cite compares two methods of administering NADH but does not
have a placebo control group.  Also, do you know if this study was of
persons with Parkinson's Disease or with any form of parkinsonism?


On 4 Apr 1997, Steve Emerson wrote:

>=20
>    Title
>           Nicotinamide adenine dinucleotide (NADH)--a new therapeutic
>           approach to Parkinson's disease. Comparison of oral and
>           parenteral application.
>          =20
>    Author
>           Birkmayer JG; Vrecko C; Volc D; Birkmayer W
>          =20

-- 
A pharmacologist who did research on NADH posted to the Parkinson's list
that the substance is not the panacea it is reported to be.  While it is
true that conventional Parkinsons meds cause many side effects, the wide
majority do have a positive, measureable affect on the disease.  
-----
Mary Ann

lambs@home.msen.com

++++++++++++++++++++++++++++++++++++
Live simply, 
   So that others may simply live (anony)
++++++++++++++++++++++++++++++++++++


M. Wallukait <mwalluka@blue.weeg.uiowa.edu> wrote in article
<Pine.A41.3.95.970404114332.148980A-100000@green.weeg.uiowa.edu>...

Do you know of any placebo controlled trials of NADH as therapy for PD?
The study you cite compares two methods of administering NADH but does not
have a placebo control group.  Also, do you know if this study was of
persons with Parkinson's Disease or with any form of parkinsonism?

Am I right in saying that this is a trial without blindness, controls
or placebo (just going from the abstract)? And presumably, the
clinical improvements cited are based on a neurologist's rating, 
not even blind (let alone objective, like finger tapping or
pronation-supination)? Lawks. 

Jeremy
-------------------------------------------------------
Jeremy Gauntlett-Gilbert
School of Psychology, 
University of St Andrews
St Andrews, Fife, 	tel:   (01334) 463053, x3053
KY16 9JU, Scotland   	email: jg3@st-and.ac.uk

:    Title
:           Nicotinamide adenine dinucleotide (NADH)--a new therapeutic
:           approach to Parkinson's disease. Comparison of oral and
:           parenteral application.
:    Author
:           Birkmayer JG; Vrecko C; Volc D; Birkmayer W
:    Address
:           Birkmayer-Institut f�r Parkinsontherapie Vienna, Austria.
:    Source
:           Acta Neurol Scand Suppl, 146:1993, 32-5
:    Abstract
:           The reduced coenzyme nicotinamide adenine dinucleotide (NADH)
:           has been used as medication in 885 parkinsonian patients in an
:           open label trial. About half of the patients received NADH by
:           intravenous infusion, the other part orally by capsules. In
:           about 80% of the patients a beneficial clinical effect was
:           observed: 19.3% of the patients showed a very good (30-50%)
:           improvement of disability, 58.8% a moderate (10-30%)
:           improvement. 21.8% did not respond to NADH. Statistical
:           analysis of the improvement in correlation with the disability
:           prior to treatment, the duration of the disease and the age of
:           the patients revealed the following results: All these 3
:           parameters have a significant although weak influence on the
:           improvement. The disability before the treatment has a positive
:           regression coefficient (t value < 0.01). The duration of the
:           disease has a negative regression coefficient (< 0.01) and so
:           has the age a negative regression coefficient (t value < 0.05).
:           In other words younger patients and patients with a shorter
:           duration of disease have a better chance to gain a marked
:           improvement than older patients and patients with longer
:           duration of the disease. The orally applied form of NADH
:           yielded an overall improvement in the disability which was
:           comparable to that of the parenterally applied form.
:           

: -- 


: Steve Emerson     semerson@teleport.com