🚀 go-pugleaf

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Postdoctoral position as posted on Postdoc Jobs website:

http://www.PostdocJobs.com
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Four postdoctoral positions are available in Virginia and Iowa working
on the functional genomics of the Arabidopsis �-glucosidase and
�-galactosidase gene families (Funded by the NSF 2010 Project). This
collaborative research between Virginia Tech (PI/PD: A. Esen) and the
University of Iowa (PI/PD: J E. Poulton) will focus on determining the
functions of approximately 75 members of two related families of
�-glycoside hydrolases. Family 1 includes �-glucosidases (EC 3.2.1.21)
and myrosinases (EC 3.2.3.1), which function in higher plants in
chemical defense against herbivores and pathogens, lignin
biosynthesis, and plant growth and development. Family 35 contains the
�-galactosidases (EC 3.2.1.23), which play key roles in fruit
ripening, flower senescence, mobilization of carbohydrate reserves,
and galactolipid turnover. Each hydrolase will be overexpressed in
foreign host (e.g. yeast and bacteria) cells and purified to determine
its biochemical properties and biological function. Natural glycosides
will be isolated primarily from Arabidopsis and related crucifers and
tested in activity assays to identify the specific substrate(s) of
each hydrolase.

All four (2 in Virginia and 2 in Iowa) positions are funded for three
years. Those who are interested in Virginia positions should contact
A. Esen whereas those interested in Iowa positions should contact J.
E. poulton.

The successful candidate for one position at each location must have
experience with basic molecular biology and biochemistry techniques,
especially protein expression in yeast and other eukaryotic host
systems, whereas the successful candidate for the other must have
experience in natural product isolation, chemistry and metabolite
profiling.


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For more information, please visit PostdocJobs website

http://www.PostdocJobs.com

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