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Article #792

Allergy or Neurogenic Response

#792
From: Betty Bridges
Date: Tue, 31 Oct 1995 00:00
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What is the difference between an allergic reaction and a neurogenic
inflammatory reaction?  Please explain in terms that a layman can
understand.  I'm a RN, but this is not a field I'm understand very
well.  Is the following situation one that might be considered a
neurogenic inflammatory response.  I started having this reaction about
7 years ago when I was working in dialysis.  Onset was sudden.  I'm not
looking for a diagnosis, just information.  I do have an appointment
with an allergist at a local teaching hospital the middle of Nov.  I'm
just trying to educate myself.

I have a severe allergy? / response to something in fragrances.  It has
nothing to do with the odor as sometimes the reaction occurs before I
can detect the odor.  I read an article about Neurogenic inflammation
triggered by Cranial Nerve V as being one theory of sensitivity to
chemicals.

My reaction is severe almost instant asthma to many (but not all)
fragranced products.  There are secondary symptoms that also occur. 
The longer the exposure the worse they are.  For example if the
fragrance causes coughing or minor wheezing rather than a life
threatening reaction and I stay around it 5 minutes or more the
secondary symptoms occur. The secondary symptoms are angioedema,
trouble thinking clearly, fatigue, and muscle / joint aches (usually
occur several hours after exposure).

The asthmatic part of the reaction responds very quickly to Proventil
inhalers and getting away from the source of the reaction.  However the
secondary symptoms last much longer.  Some of symptoms such as the
angioedema and fatigue are ones I also have to some of the things I'm
allergic to such as mites, molds, and food allergies.

Thanks for the info......educating myself gives me the illusion of
having some control over something I have no control over.  :-)

Betty
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From: bcb56@ix.netcom.com (Betty Bridges )
Subject: Allergy or Neurogenic Response
Date: 1995/10/31
Message-ID: <4752gv$esg@ixnews3.ix.netcom.com>
X-Deja-AN: 118368102
organization: Netcom
x-netcom-date: Tue Oct 31  3:49:51 AM PST 1995
newsgroups: sci.research,bionet.immunology,sci.med.occupational,alt.support.asthma